Medication review in inpatients at cardiology clinic / Prehodnotenie terapie u hospitalizovaných pacientov na kardiologickej klinike

Kováčová, Barbora; Hasilla, Jozef; A, Durisová

doi:10.1515/afpuc-2015-0002

Cited by 2 publications

(1 citation statement)

References 9 publications

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“…In hospital settings, DRPs may occur due to the complexity of treatment protocols, initiation or cessation of new medications, using high-alert medications, inappropriate use of medications, and many other reasons 23 24. The prevalence of DRPs was previously reported at between 33–99% in hospital regardless of wards,6 8 of which 1.7–2.6 per patient occurred8 in medical wards and 0.72–2.14 per patient occurred in surgical wards 8 25.…”

Section: Discussionmentioning

confidence: 99%

Drug-related problems at the heart of cardiac surgery

et al. 2023

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ObjectivesOptimal perioperative success in cardiac surgery requires precise management of drug treatment. This study aimed to determine the prevalence, types and associated factors of drug-related problems (DRPs) during the entire hospital stay.MethodsA prospective observational study was conducted at the department of cardiovascular surgery in a university hospital between November 2019 and March 2020. Patients with planned elective cardiac surgery, aged ≥18 years, were included. A clinical pharmacist collaboratively reviewed medications on a daily basis and identified DRPs.ResultsA total of 100 patients (60 male) were included; median (range) age was 62 (19–86) years, and median (IQR) length of stay in hospital was 15 (9) days. A total of 275 DRPs were identified (median (IQR) 3 (2–4)). The number of patients who had at least one DRP was 47 preoperatively, 55 in the postoperative intensive care unit, 100 in the postoperative ward, and 16 at discharge. In order to reduce bias because of the small sample size, Firth’s logistic regression analysis was conducted. Statistically significant variables according to univariate analysis were included into a logistic regression model. Therefore the length of hospital stay (OR 1.14, 95% CI 1.03 to 1.26, p=0.008), living arrangements (living alone) (OR 4.24, 95% CI 1.41 to 12.73, p=0.009), number of medications at admission (OR 1.32, 95% CI 1.09 to 1.59, p=0.002), and having coronary artery bypass graft surgery (OR 2.87, 95% CI 1.07 to 7.70, p=0.03) were associated with an increased risk for DRPs in the final model.ConclusionHospital stay carries an increased risk for DRPs, especially at the postoperative stage. Modifiable risk factors for DRPs can be managed by required interventions performed by a multidisciplinary healthcare team.

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Section: Discussionmentioning

confidence: 99%

Drug-related problems at the heart of cardiac surgery

et al. 2023

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Introducing clinical pharmacy services to cardiovascular clinics at a university hospital in Northern Cyprus

Al-Baghdadi¹,

Al-Baghdadi

Abdi³

et al. 2017

Int J Clin Pharm

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Background Clinical pharmacists are the primary source of scientifically valid information and advice on the safe, rational, and cost-effective use of medications. However, ward-based clinical pharmacy services are not well optimized in Northern Cyprus. Objective Ward based clinical pharmacy services were introduced and evaluated in cardiovascular clinics. Setting Cardiology and cardiovascular surgery departments in a tertiary university hospital. Methods A prospective interventional study introduced and documented clinical pharmacy services for 120 days. Drug-related problems were classified using the Pharmaceutical Care Network Europe PCNE DRP classification tool V6.2. Main outcome measure Interventions proposed and acceptance rate of recommendations. Results A total of 133 patients were reviewed, and, 81 patients had drug-related problems. Only 402 (93.1%) of the 432 suggested interventions were accepted and regarded as clinically relevant. Drug-related problems primarily involved antihypertensive, diuretic, and antithrombotic agents. Treatment effectiveness was the major type of drug-related problems (107; 49.3%) followed by adverse drug reactions (74; 34.1%). Drug dose and selection were the most frequent causes of drug-related problems. Add/change/stop medications were the most common types of intervention at the prescriber level. A total of 171 (78.8%) of the identified 217 drug-related problems were solved, 4 (1.8%) of the problems were partially solved, 32 (14.7%) problems were unsolved, and 10 (4.6%) problems had unknown outcomes. Conclusion Clinical pharmacy services may have optimized therapy effectiveness and prevent adverse effects. The pharmacist interventions were highly accepted by cardiologists; this may indicate the presence of a great opportunity and need to optimize and implement CPS in other hospitals in Northern Cyprus.

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Medication review in inpatients at cardiology clinic / Prehodnotenie terapie u hospitalizovaných pacientov na kardiologickej klinike

Cited by 2 publications

References 9 publications

Drug-related problems at the heart of cardiac surgery

Drug-related problems at the heart of cardiac surgery

Introducing clinical pharmacy services to cardiovascular clinics at a university hospital in Northern Cyprus

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