Medication-related quality of life (MRQoL) in ambulatory older adults with multi-morbidity and polypharmacy

Jennings, Emma; O’Mahony, Denis; Gallagher, Paul

doi:10.1007/s41999-021-00573-6

Cited by 7 publications

(2 citation statements)

References 15 publications

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“…Age was a factor in health-related quality of life among polypharmacy patients, as reported by Jennings et al . [ 15 ]. Based on their accounts, an ambulatory older patient cohort attending a specialist hospital-based geriatric medicine outpatient clinic experienced baseline polypharmacy and multimorbidity and reported poor age-adjusted health-related quality of life (HRQoL).…”

Section: Discussionmentioning

confidence: 99%

“…For example, drug interactions can cause side effects that negatively affect the patient physically [ 12 , 13 ]. Polypharmacy is linked to poor health outcomes, such as medication nonadherence, adverse pharmacological effects, and decreased quality of life (QoL) [ 14 , 15 ]. The guidelines for hospitalized individuals with multimorbidity and long-term medication use require frequent reviews to improve QoL.…”

Section: Introductionmentioning

confidence: 99%

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Prevalence of polypharmacy and medication-related quality of life among adult patients in Al-Ahsa, Saudi Arabia

Almuhanna,

Alnaim,

AlHussain

et al. 2023

JMedLife

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Polypharmacy, often defined as the concurrent use of five or more medications, has become increasingly common due to various factors, including shifts in lifestyle and a rise in health-related issues among individuals. However, using multiple medications could bring more issues to the patient, as it is linked to poor health outcomes, including medication nonadherence, adverse pharmacological effects, and decreased quality of life (QoL). This study aimed to determine the prevalence of polypharmacy and identify drug-related problems among adult patients in Al-Ahsa. A cross-sectional study was conducted among adult patients living in Al-Ahsa, Saudi Arabia, taking five or more medications. A self-administered questionnaire was distributed among the target population using an online survey. The questionnaire included sociodemographic data (i.e., age, sex, education, etc.), a questionnaire to assess behaviors regarding the use of polypharmacy, and a 10-item questionnaire to measure medication-related quality of life (MRQoL). In total, 196 of the 1,088 patients surveyed took five or more medications, indicating an 18% prevalence of polypharmacy. Among the 196 patients, 26.5% reported poor medication-related QoL. In univariate analysis, sex, occupational status, average monthly income, hypertension, asthma, difficulty managing medications, and side effects experienced were significantly associated with MRQoL. Independent significant predictors of poor MRQoL were having asthma and difficulty managing medications. The prevalence of poor medication-related quality of life among adult patients in our region was 26.5%, lower than that in previous studies. Poor MRQoL was associated with lower monthly income, hypertension, asthma, side effects, and difficulty managing medications.

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Section: Discussionmentioning

confidence: 99%