Medication-related problems occurring in people with diabetes during an admission to an adult teaching hospital: A retrospective cohort study

Claydon-Platt, Kate; Manias, Elizabeth; Dunning, Trisha

doi:10.1016/j.diabres.2012.03.003

Cited by 31 publications

(30 citation statements)

References 33 publications

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“…In our study, 22.1% of patients with diabetes were identified with CKD, which was 4.8‐fold higher than that in the overall population with metabolic disorders, but was much less than the 63.9% prevalence among T2DM patients in the downtown area of Shanghai city of China . And it was similar with the findings of other studies on hospitalized patients (17.7%) . It suggested that CKD might be common among hospitalized patients, and could be a potential reason for hospitalization of patients with diabetes.…”

Section: Discussionsupporting

confidence: 87%

Study design and baseline characteristics of inpatients with diabetes mellitus in a tertiary hospital in China: A database study based on electronic medical records

et al. 2018

J Evidence Based Medicine

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Section: Discussionsupporting

confidence: 87%

Study design and baseline characteristics of inpatients with diabetes mellitus in a tertiary hospital in China: A database study based on electronic medical records

et al. 2018

J Evidence Based Medicine

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“…Existing literature suggests that marriage is associated with lower mortality in male patients hospitalized for pneumonia, 13 and also with fewer hospitalizations related to medication errors in diabetes. 14 In our study, being married was associated with fewer cirrhosis-related hospital admissions, a longer time to hospital admission, and a lower risk of cirrhosis-related death. It is not clear how this effect is mediated.…”

Section: Discussionsupporting

confidence: 46%

Advanced Disease, Diuretic Use, and Marital Status Predict Hospital Admissions in an Ambulatory Cirrhosis Cohort

et al. 2013

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Background and Aims Hospital admissions in cirrhotic patients are a source of significant health care expenditure. Most studies to date have focused on readmissions in patients with decompensated cirrhosis. We sought to describe predictors of hospital admissions in an ambulatory cirrhosis cohort consisting of both compensated and decompensated patients to identify patients who could benefit from intensified outpatient chronic disease management. Methods We performed a retrospective cohort study of 395 cirrhotic patients followed at an academic medical center liver clinic. Inclusion criteria were documented cirrhosis and longitudinal care at our center during 2006–2008. Patients were followed until December 2011, death, or liver transplantation. The primary outcomes were non-elective cirrhosis-related hospital admissions within one year and time to admission. The secondary outcome was two-year cirrhosis-related mortality. The study was approved by the Partners Human Research Committee (protocol 2012P001912). Results Seventy-eight patients (19.7%) had at least one cirrhosis-related hospital admission within one year. The following were significant predictors in the multivariable model: Model for End-Stage Liver Disease (MELD) score ≥ 15 (OR 2.22, 95% CI [1.21–4.07], p=0.01), diagnosis of hepatocellular carcinoma (HCC) (3.64 [1.42–9.35], 0.007), diuretic use (2.27 [1.23–4.17], 0.008), at least one cirrhosis-related admission during the baseline year (2.17 [1.21–3.89], 0.01), and being unmarried (1.92 [1.10–3.35], 0.02). Conclusions Advanced disease, diuretic use, and marital status were associated with cirrhosis-related hospital admissions in patients followed at an academic medical center liver clinic. Our findings suggest that patients with inadequately or overzealously treated ascites, as well as those with limited social supports, could benefit from intensified outpatient management.

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“…Many of the studies we found in adult patients combined errors and non-adherence together as “drug-related problems”; this approach makes it difficult to identify different causes, effects, and interventions for each. 12, 23, 24 However, the interaction between error and non-adherence in individual patients can change the type of adverse outcomes seen. For example, adult patients on warfarin experienced under coagulation with non-adherence but over-coagulation or under-coagulation with adherence and error.…”

Section: Discussionmentioning

confidence: 99%

“…More than half of these (64%) were medication errors with unintentional overdoses causing hypoglycemia. 12 In order to understand whether human error theory could explain nonadherence, Barber et. al.…”

Section: Introductionmentioning

confidence: 99%

Errors and Nonadherence in Pediatric Oral Chemotherapy Use

Walsh¹,

Ryan²,

Daraiseh³

et al. 2016

Oncology

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Background: Nonadherence and medication error both limit the effectiveness of oral chemotherapy. The overlap between nonadherence and medication error is not well studied in children, and interventions strategies differ for each. Our objective was to describe nonadherence and errors in children with cancer to inform future interventions. Methods: Nonadherence was measured using two self-report tools. Medication error was measured using medication review and observation of administration at home. Two clinicians made judgments about whether each error also represented an episode of nonadherence. Results: Of 72 errors detected in 92 home visits, 27 were also instances of nonadherence. For example, parents gave a child 1 tablet of mercaptopurine every day rather than the prescribed 1 tablet 5 days a week and ½ tablet on weekends. Clinician reviewers judged that family interventions and health system interventions would be most effective in preventing the errors and nonadherence identified in this population of children with cancer. Discussion: The relationship between medication errors and nonadherence is not well described in the literature. Our data indicate that medication error and nonadherence coexist in the same population and in the same patient. Interventions should address both to most effectively support self-management.

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Medication-related problems occurring in people with diabetes during an admission to an adult teaching hospital: A retrospective cohort study

Cited by 31 publications

References 33 publications

Study design and baseline characteristics of inpatients with diabetes mellitus in a tertiary hospital in China: A database study based on electronic medical records

Study design and baseline characteristics of inpatients with diabetes mellitus in a tertiary hospital in China: A database study based on electronic medical records

Advanced Disease, Diuretic Use, and Marital Status Predict Hospital Admissions in an Ambulatory Cirrhosis Cohort

Errors and Nonadherence in Pediatric Oral Chemotherapy Use

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