Medication-related factors of non adherence among patients with schizophrenia and bipolar disorder: Outcome of a cross-sectional survey in Maiduguri, North-eastern Nigeria

Ibrahim, Kamarulzaman; W, A; Pindar,; K, None S; Yerima,; M, M; Rabbebe,; B, I; Shehu,; S,; Garkuwa,; Do, H A; Bashir,; Y., Ichihara Maria; Wakil,; A, M; Yahya, Yahya Yahya; J, S

doi:10.5897/jnbh2015.0128

Cited by 20 publications

(31 citation statements)

References 36 publications

(34 reference statements)

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“…The management of BD, especially BP-II, includes both pharmacological and non-pharmacological interventions in the acute phases of mania (or hypomania), in depressive episodes, as well as for long-term therapy to prevent recurrences [69][70][71]125,139]. Given the difficulties, several screening instruments have been developed to aid diagnosis; however, concerns have been raised with their sensitivity, especially in community settings [69,140].…”

Section: Current Management Approaches For Patients With Bd Especiallmentioning

confidence: 99%

“…Pharmacological interventions are seen as the cornerstone for managing acute mania or for those who suffer a manic episode while on long-term treatment [70,90,125,139]. Lithium was the first treatment used for the management of acute mania [69,96,141,142].…”

Section: Current Management Approaches For Patients With Bd Especiallmentioning

confidence: 99%

“…In addition, prescribers must be cognizant of the weight gain potential with antipsychotic medicines such as olanzapine versus for instance risperidone and quetiapine (moderate weight gain potential) and aripiprazole (low weight gain potential) [153]. Co-morbidities are a particular issue in patients with BD as adherence to therapies is already a concern [125,139]. This will be a particular issue in patients with both mental disorders and HIV necessitating additional psychosocial support [9,53,154,155], with high rates of HIV seen in sub-Saharan Africa [154].…”

Section: Current Management Approaches For Patients With Bd Especiallmentioning

confidence: 99%

“…• Issues of polypharmacy and adherence remain as additional critical concerns in the effective management of BD in Nigeria alongside copayments [39,139,176,177].…”

Section: Nigeriamentioning

confidence: 99%

“…For instance, there is only one neuro-psychiatric hospital for over four million people in the Niger Delta region of Nigeria [209]. • There are also issues with affordability of the medications for patients with mental health disorders [139,209,210].…”

Section: Nigeriamentioning

confidence: 99%

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Pharmacotherapeutic interventions for bipolar disorder type II: addressing multiple symptoms and approaches with a particular emphasis on strategies in lower and middle-income countries

Godman

Grobler

Van-De-Lisle

et al. 2019

Expert Opinion on Pharmacotherapy

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Introduction: Appropriately managing mental disorders is a growing priority across countries in view of the impact on morbidity and mortality. This includes patients with bipolar disorders (BD). Management of BD is a concern as this is a complex disease with often misdiagnosis, which is a major issue in lower and middleincome countries (LMICs) with typically a limited number of trained personnel and resources. This needs to be addressed. Areas covered: Medicines are the cornerstone of managing patients with Bipolar II across countries including LMICs. The choice of medicines, especially antipsychotics, is important in LMICs with high rates of diabetes and HIV. However, care is currently compromised in LMICs by issues such as the stigma, cultural beliefs, a limited number of trained professionals and high patient co-payments. Expert opinion: Encouragingly, some LMICs have introduced guidelines for patients with BD; however, this is very variable. Strategies for the future include addressing the lack of national guidelines for patients with BD, improving resources for mental disorders including personnel, improving medicine availability and patients' rights, and monitoring prescribing against agreed guidelines. A number of strategies have been identified to improve the treatment of patients with Bipolar II in LMICs, and will be followed up.

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Section: Current Management Approaches For Patients With Bd Especiallmentioning

confidence: 99%

Section: Current Management Approaches For Patients With Bd Especiallmentioning

confidence: 99%

Section: Current Management Approaches For Patients With Bd Especiallmentioning

confidence: 99%

“…• Issues of polypharmacy and adherence remain as additional critical concerns in the effective management of BD in Nigeria alongside copayments [39,139,176,177].…”

Section: Nigeriamentioning

confidence: 99%

Section: Nigeriamentioning

confidence: 99%

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Pharmacotherapeutic interventions for bipolar disorder type II: addressing multiple symptoms and approaches with a particular emphasis on strategies in lower and middle-income countries

Godman

Grobler

Van-De-Lisle

et al. 2019

Expert Opinion on Pharmacotherapy

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Religiosity and treatment adherence among out-patients with schizophrenia

Amadi

Aguocha

Attama

et al. 2021

Mental Health, Religion & Culture

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Tramadol control measures and supply for health-care services: findings from Ghana and other West African countries

Ane

2023

DHS

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Purpose This paper aims to explore the role of tramadol in pain management and the impact of regulatory measures on supply and medical access in Ghana and other African countries. Design/methodology/approach The study adopted an exploratory design and qualitative methods to explore the perspectives of different actors, including officials of regulatory agencies, law enforcement agents, health-care providers and non-medical tramadol users. Data were collected through individual and group interviews, and transcripts were subjected to thematic analysis. Findings Findings show that tramadol fills a critical gap in treating pain across Ghana in areas with an acute shortage of opioid analgesics due to scheduling-related barriers. This was partly due to porous borders allowing for an influx of tramadol into the countries. The study further found that most tramadol purchases in Ghana and other West African countries were made from market traders rather than from health-care settings and were mainly generic medicines categorised as “substandard/spurious/falsely-labelled/falsified/counterfeit medical products” within the World Health Organization standards. Research limitations/implications Although the findings are instructive, there were some limitations worth noting. The study encountered several limitations, especially with the non-medical users, because the environment is highly criminalised, People who use drugs were unwilling to avail themselves for fear of law enforcement officers’ harassment. Obtaining ethical clearance had its own bureaucracy – challenges that delayed the study time frame. Practical implications Placing tramadol under the list of internationally controlled substances would create barriers to access to effective pain medications, particularly by the poor, and encourage victimisation of users by law enforcement authorities. Originality/value The study is based on empirical research on tramadol use and regulation in African countries, contributing to knowledge in an under-researched subject area on the continent. The comparative approach further adds value to the research.

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Medication-related factors of non adherence among patients with schizophrenia and bipolar disorder: Outcome of a cross-sectional survey in Maiduguri, North-eastern Nigeria

Cited by 20 publications

References 36 publications

Pharmacotherapeutic interventions for bipolar disorder type II: addressing multiple symptoms and approaches with a particular emphasis on strategies in lower and middle-income countries

Pharmacotherapeutic interventions for bipolar disorder type II: addressing multiple symptoms and approaches with a particular emphasis on strategies in lower and middle-income countries

Religiosity and treatment adherence among out-patients with schizophrenia

Tramadol control measures and supply for health-care services: findings from Ghana and other West African countries

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