Medication-induced Uveitis: An Update

Iqbal, Kashif; Hay, Madeline; Emami-Naeini, Parisa

doi:10.18502/jovr.v16i1.8254

Cited by 5 publications

(5 citation statements)

References 56 publications

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“…İlaca bağlı üveite sebep olduğu bilinen birçok topikal, intraoküler ve sistemik ilaç mevcuttur. [19] Naranjo algoritmasına göre üveite neden olduğu düşünülen ilaçların özetlendiği liste ve üveit gelişimini tetikleme olasılıklarının nicel değerlendirmesi Tablo 2' de verilmiştir. Bu derlemede, rifabutin, sidofovir, prokainamid, ritonavir ve prostaglandin (PG) analoglarına bağlı gelişen üveitlerden bahsedilecektir.…”

Section: Ilaç Ilişkili üVeite Neden Olan Ajanlarunclassified

Drugs Causing Uveitis: Pathogenesis, Diagnosis and Treatment

2023

Güncel Retina (Current Retina)

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Drug-induced uveitis, which may result from systemic, periocular, intraocular, and topical application of certain drugs, has been covered extensively in numerous publications over the last decade. The dose and duration of the drug and other drugs used simultaneously may be determinative in the development of the uveitis. Drug-induced uveitis, which is rare and can occur in a wide clinical spectrum from mild to severe, usually regresses rapidly with accurate diagnosis and discontinuation of the relevant drug. Therefore, it is important for clinicians to be aware of the drugs that cause uveitis.

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Section: Ilaç Ilişkili üVeite Neden Olan Ajanlarunclassified

Drugs Causing Uveitis: Pathogenesis, Diagnosis and Treatment

2023

Güncel Retina (Current Retina)

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“…Common systemic drugs which may cause uveitis are Cidofovir, Rifabutin, Fluoroquinolones, bisphosphonates, immune checkpoint inhibitors, protein kinase inhibitors and sulfonamides. Mechanism may be toxic or immune mediated ( 59 , 60 ).…”

Section: Non-infectious Uveitismentioning

confidence: 99%

“…Protein kinase inhibitors have been linked to all types of uveitis and are responsive to topical steroids. Drug-induced Vogt-Koyanagi-Harada syndrome has also been described in association with the use of some protein kinase inhibitors ( 60 ).…”

Section: Non-infectious Uveitismentioning

confidence: 99%

Pediatric uveitis: Role of the pediatrician

et al. 2022

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The challenges of childhood uveitis lie in the varied spectrum of its clinical presentation, the often asymptomatic nature of disease, and the evolving nature of the phenotype alongside normal physiological development. These issues can lead to delayed diagnosis which can cause significant morbidity and severe visual impairment. The most common ocular complications include cataracts, band keratopathy, glaucoma, and macular oedema, and the various associated systemic disorders can also result in extra-ophthalmic morbidity. Pediatricians have an important role to play. Their awareness of the various presentations and etiologies of uveitis in children afford the opportunity of prompt diagnosis before complications arise. Juvenile Idiopathic Arthritis (JIA) is one of the most common associated disorders seen in childhood uveitis, but there is a need to recognize other causes. In this review, different causes of uveitis are explored, including infections, autoimmune and autoinflammatory disease. As treatment is often informed by etiology, pediatricians can ensure early ophthalmological referral for children with inflammatory disease at risk of uveitis and can support management decisions for children with uveitis and possible underling multi-system inflammatory disease, thus reducing the risk of the development of irreversible sequelae.

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“…[ 60 ] Although effective in treating rheumatologic conditions, it is not commonly used for uveitis as it is not as efficacious in comparison to other anti-TNF-a agents, [ 60 ] and there is risk for drug-induced uveitis and sarcoidosis. [ 61 , 62 ]…”

Section: Introductionmentioning

confidence: 99%

“…[ 70 , 71 , 72 ] It has been studied in uveitis associated with BD and noninfectious scleritis. [ 62 ][ 63 , 64 ][ 73 ] Although rapid control of BD-related uveitis was noted in the pilot and phase-2 studies, [ 70 , 71 ] the phase-3 EYEGUARD-B trial failed to meet its primary endpoint and the medicine did not significantly alter the risk of flares. [ 72 ]…”

Section: Introductionmentioning

confidence: 99%

A Review of Systemic Biologics and Local Immunosuppressive Medications in Uveitis

Mehta

Emami-Naeini

2022

JOVR

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Uveitis is one of the most common causes of vision loss and blindness worldwide. Local and/or systemic immunosuppression is often required to treat ocular inflammation in noninfectious uveitis. An understanding of safety and efficacy of these medications is required to individualize treatment to each patient to ensure compliance and achieve the best outcome. In this article, we reviewed the effectiveness of systemic biologic response modifiers and local treatments commonly used in the management of patients with noninfectious uveitis.

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Medication-induced Uveitis: An Update

Cited by 5 publications

References 56 publications

Drugs Causing Uveitis: Pathogenesis, Diagnosis and Treatment

Drugs Causing Uveitis: Pathogenesis, Diagnosis and Treatment

Pediatric uveitis: Role of the pediatrician

A Review of Systemic Biologics and Local Immunosuppressive Medications in Uveitis

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