Medication in elderly people: its influence on salivary pattern, signs and symptoms of dry mouth

Leal, Soraya Coelho; Bittar, Juliana Duarte; Portugal, Aline; Falcão, Denise Pinheiro; Faber, Jorge; Zanotta, Pedro

doi:10.1111/j.1741-2358.2009.00293.x

Cited by 73 publications

(84 citation statements)

References 20 publications

(34 reference statements)

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“…As this was a pilot-study, further studies with a larger number of participants, including elderly individuals, in whom salivary problems are more prevalent (17), should be done to confirm these preliminary results and lead to recommendation of its large-scale use. …”

Section: Discussionmentioning

confidence: 74%

Use of graduated syringes for measuring salivary flow rate: a pilot study

et al. 2010

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The evaluation of the salivary flow rate is important in several situations of dental practice. However, weighing the collected salivary volume it is not a practical method in public health services. This work evaluated the use of hypodermic graduated syringes as a simpler alternative method to measure the salivary flow rate. Saliva samples were obtained from 50 individuals (31 females and 19 males) aged 8 to 32 years (mean age: 12.4 years), recruited at the outpatient dental clinics of two public health centers. After collection, the saliva was weighed in a graduated scale and the results compared with the volume obtained through its measurement, in mL, in graduated hypodermic syringes. There was a positive and significant relationship between the two methods of measuring salivary flow rates as demonstrated by the Pearson's correlation coefficient (r = 0.996, with p<0.05). Measurement of the salivary flow rate using graduated syringes demonstrated to be a reliable method, with lower cost and more practical than the traditional method of salivary weighing.

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Section: Discussionmentioning

confidence: 74%

Use of graduated syringes for measuring salivary flow rate: a pilot study

et al. 2010

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“…Th ese results are consistent with the results of an investigation conducted among nursinghome residents in Holland, which found low salivary fl ow rates in 72% of the institutionalized elderly 26 . Salivary gland hypofunction may be correlated with various systemic disorders, medications, as well as the number of medications 3,11,27,28 . Th e higher incidence of decreased salivary fl ow rate which we found in the group of institutionalized elderly could be the result of a rather high number of diff erent medications or intake of medications with specifi c xerostomic side effects 27,28 .…”

Section: Discussionmentioning

confidence: 99%

“…Salivary gland hypofunction may be correlated with various systemic disorders, medications, as well as the number of medications 3,11,27,28 . Th e higher incidence of decreased salivary fl ow rate which we found in the group of institutionalized elderly could be the result of a rather high number of diff erent medications or intake of medications with specifi c xerostomic side effects 27,28 . Regardless of the etiology of salivary gland hypofunction, changes in the oral ecology occur with unstimulated whole saliva fl ow rates below 0.20 mL per minute 15 .…”

Section: Discussionmentioning

confidence: 99%

Salivary Flow Rate, Oral Yeast Colonization and Dental Status in Institutionalized and Non-Institutionalized Elderly

Glažar

2016

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SUMMARY -Elderly people, especially those institutionalized in long-term care facilities, are at risk of various oral diseases. Th e aim of the study was to determine the incidence of hyposalivation and colonization/oral fungal infection of oral cavity with yeasts, as well as dental status in institutionalized and non-institutionalized elderly. Th e study included 280 institutionalized and 61 non-institutionalized elderly people. Salivary fl ow rate, oral colonization with yeasts/oral infection and dental status were assessed and compared between the groups. Th e institutionalized elderly had a signifi cantly lower salivary fl ow rate (p=0.035). Oral colonization with yeasts was more frequently found in institutionalized elderly (p<0.001) as compared with non-institutionalized elderly. A negative correlation was found between decreased salivary fl ow rate and oral yeast colonization and oral fungal infection in both the institutionalized (rs=-0.58; p<0.05) and non-institutionalized (rs=-0.52; p<0.05) groups. A signifi cant diff erence in DMFT index was observed between the two groups (p<0.001). A negative correlation between decreased salivary fl ow rate and dental status was found in both the institutionalized (rs=-0.22; p<0.05) and non-institutionalized (rs=-0.56; p<0.05) groups. Th e results revealed a signifi cantly higher level of hyposalivation and oral yeast colonization and poorer dental status in the institutionalized group as compared with the non-institutionalized group of elderly people.

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“…Several bioarchaeological investigations have also revealed increases in the frequency of periodontal disease with age in past populations (e.g., Costa, 1982;Kerr, 1991Kerr, , 1994Hillson, 1996;Oztunc et al, 2006). In some cases, the relationship between age and periodontal disease in modern populations is at least partly explained by behavioral factors, such as changes in oral hygiene or the increased use of medications that reduce salivary flow (Abdellatif and Burt, 1987;Sjögren and Nordström, 2000;Leal et al, 2010). However, some researchers have found that the significant relationship between age and periodontal disease persists when other factors, such as oral hygiene, are controlled for (Streckfus et al, 1999).…”

Section: Discussionmentioning

confidence: 99%

The association between periodontal disease and periosteal lesions in the St. Mary Graces cemetery, London, England A.D. 1350-1538

DeWitte

Bekvalac

2011

Am. J. Phys. Anthropol.

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Numerous studies have demonstrated significant associations between periodontal disease and many other diseases in living populations, and some studies have shown that individuals with periodontal disease are at elevated risks of mortality. Recent analysis of a medieval skeletal sample from London has also shown that periodontal disease was associated with increased risks of mortality in the past. This study examines whether periodontal disease is associated with periosteal lesions in a skeletal sample from the urban St. Mary Graces cemetery (n = 265) from medieval London. The results reveal a significant association between periodontal disease and periosteal lesions in the St. Mary Graces sample (i.e., individuals with periodontal disease were also likely to have periosteal lesions), and the association between the two is independent of age. The association between the two pathological conditions might reflect underlying reduced immune competence and thus heightened susceptibility to pathogens that cause periodontal disease or periosteal lesions, exposure to an environmental factor, or underlying heightened inflammatory responses.

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Medication in elderly people: its influence on salivary pattern, signs and symptoms of dry mouth

Abstract: The use of medication increases the chance that an elderly person may present signs related to xerostomia and alterations in stimulated saliva flow and buffering capacity.

Cited by 73 publications

References 20 publications

Use of graduated syringes for measuring salivary flow rate: a pilot study

Use of graduated syringes for measuring salivary flow rate: a pilot study

Salivary Flow Rate, Oral Yeast Colonization and Dental Status in Institutionalized and Non-Institutionalized Elderly

The association between periodontal disease and periosteal lesions in the St. Mary Graces cemetery, London, England A.D. 1350-1538

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