Medication contaminants as a potential cause of anaphylaxis to vincristine: What about drug‐specific antigens?

Reply to: Medication contaminants as a potential cause of anaphylaxis to vincristine: What about drug specific antigens?

“…We appreciate the informative letter by Dr. Nicholas Kounis and colleagues in response to our manuscript entitled “Medication contaminants as a potential cause of anaphylaxis to vincristine.” Kounis et al. propose some questions about our report and discuss it broadly in the context of drug allergy . They first note that vincristine has been associated with allergic reactions of the Kounis type, which are characterized by acute myocardial infarction .…”

“…Dr. Kounis et al propose some questions about our report, and discuss it broadly in the context of drug allergy [2]. They first note that vincristine has been associated with allergic reactions of the Kounis type, which are characterized by acute myocardial infarction [3–5].…”