Medication compliance among children

Dawood, Omar Thanoon; Izham, Mohamed; Palaian, Subish

doi:10.1007/s12519-010-0218-8

Cited by 24 publications

(20 citation statements)

References 15 publications

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“…The emotional wellbeing of the patient is equally important in treatment adherence as it shapes and guides the action and behaviour of the patient [9] . Non-adherence to a medical regimen is a concern in the treatment of paediatric malignancies, not least in the developing countries [10] , since it can have significant adverse health outcomes in children and adolescents with cancer [4,8] . Refraining from taking or incorrectly taking cancer medications can bring about serious health and economic outcomes for the individual child and the wider society [11,12] .…”

Section: Introductionmentioning

confidence: 99%

Adherence to medication: A nation-wide study from the Children’s Cancer Hospital, Egypt

Malla

Helm²,

Wilderäng³

et al. 2013

WJP

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AIM:To investigate adherence to medical regimen and predictors for non-adherence among children with cancer in Egypt. METHODS:We administered two study specific questionnaires to 304 parents of children diagnosed with cancer at the Children's Cancer Hospital in Cairo, Egypt, one before the first chemotherapy treatment and the other before the third. The questionnaires were translated to colloquial Egyptian Arabic, and due, to the high illiteracy level in Egypt an interviewer read the questions in Arabic to each parent and registered the answers. Both questionnaires consisted of almost 90 questions each. In addition, a Case Report Form was filled in from the child's medical journal. The study period consisted of 7 mo (February until September 2008) and we had a participation rate of 97%. Descriptive statistics are presented and Fisher's exact test was used to check for possible differences between the adherent and non-adherent groups. A P -value below 0.05 was considered significant. Software used was SAS version 9.3 for Windows (SAS Institute Inc., Cary, NC, United States). RESULTS:Two hundred and eighty-one (90%) parents answered the second questionnaire, regarding their child's adherence behaviour. Approximately two thirds of the children admitted to their third chemotherapy treatment had received medical recommendations upon discharge from the first or second chemotherapy treatment (181/281, 64%). Sixty-eight percent (123/181) of the parents who were given medical recommendations reported that their child did not follow the recommendations. Two main predictors were found for non-adherence: child resistance (111/123, 90%) and inadequate information (100/123, 81%). In the adherent group, 20% of the parents (n = 12/58) reported trust in their child's doctor while 14 percent 8/58 reported trust in the other health-care professionals. Corresponding numbers for the non-adherent group are 8/123 (7%) for both their child's doctor and other health-care professionals. Almost all of the parents expressed a lack of optimism towards the treatment (116/121, 96%), yet they reported an intention to continue with the treatment for two main reasons, for the sake of their child's life (70%) (P = 0.005) and worry that their child would die if they discontinued the treatment (81%) (P < 0.0001). CONCLUSION:Non-adherence to medical regimen is common among children diagnosed with cancer in BRIEF ARTICLE 25June 22, 2013|Volume 3|Issue 2| WJP|www.wjgnet.com Egypt, the main reasons being child resistance and inadequate information.© 2013 Baishideng. All rights reserved.Key words: Cancer; Adherence to medical regimen; Non-compliance; Patient-physician communication; Paediatric oncology; Psycho-oncology; Psychosocial Core tip: Ensuring adherence to a prescribed medication regimen is a complex problem, even in parts of the world where studies have been made. Such studies have not been made in the Arab World. Research has established that a holistic approach is essential if adherence is to be improved. We know that patient-physici...

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Section: Introductionmentioning

confidence: 99%

Adherence to medication: A nation-wide study from the Children’s Cancer Hospital, Egypt

Malla

Helm²,

Wilderäng³

et al. 2013

WJP

View full text Add to dashboard Cite

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“…К сожалению, многочисленные исследования и отче-ты врачей указывают на сложности достижения компла-ентности в педиатрии [3][4][5].…”

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“…При снижении качества жизни, связан-ном с хроническим заболеванием, больные также могут проявлять низкую приверженность к лечению: у 30-60% пациентов с хроническими заболеваниями (энурез, эпилепсия, астма, диабет, атопический дерматит и др.) отмечена низкая степень соблюдения врачебных пред-писаний из-за длительности лечения, многочисленно-сти препаратов и периодов симптоматической ремиссии [4]. Национальный институт детского здравоохранения и развития человека США учредил программу исследо-ваний, касающихся поведенческих аспектов в педиатрии и охране здоровья.…”

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“…Очевидно, что влияние различных факторов на фор-мирование комплаентности раскрывается в их взаи-мосвязи. Ни один из них по отдельности не оказывает определяющего влияния на комплаентность [4].…”

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“…Исследование, проведенное сре-ди родителей детей с астмой, продемонстрировало, что низкая комплаентность ассоциируется с беспокойством родителей из-за использования препаратов контроля. Родители могли прекратить ежедневную ингаляцию, если ребенок чувствовал себя лучше, полагая, что так они предупреждают развитие негативных последствий от использования медикаментов [4]. Длительность тече-ния заболеваний, многочисленные препараты и сложные приемы их дозирования, опасения побочных действий лекарств, необходимость поддерживающей противоре-цидивной терапии негативно сказываются на привер-женности к лечению, таким образом, оказывая большое влияние на качество жизни родственников больного.…”

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