Medication adherence: Factors influencing compliance with prescribed medication plans

Vlasnik, Jon; Aliotta, Sherry; DeLor, Bonnie

doi:10.1016/j.casemgr.2005.01.009

Cited by 129 publications

(121 citation statements)

References 40 publications

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“…Common barriers to medication adherence include poor patient-health care provider communication, inadequate patient knowledge about medications, low health literacy, patient skepticism of the need for treatment, fear of adverse drug effects, and patients' experiences of symptom-free periods. 16,17 Objectives That being said, the increased understanding of health conditions and medication knowledge should influence patients to adhere to their medication regimens. Additionally, more frequent bi-directional communication between patients and health care providers, aided by electronic communication, could reinforce patients' adherence to their treatment plans.…”

Section: Health Information Technologymentioning

confidence: 99%

The Use of Electronic Personal Health Records to Improve Medication Adherence and Patient Engagement: A Randomized Study of Non-valvular Atrial Fibrillation Patients

Chen¹,

Roebuck²,

Sami³

et al. 2017

J Innov Cardiac Rhythm Manage

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ABSTRACT. Embolic stroke is a major complication of atrial fibrillation (AF) that frequently results in disability or death. The administration of oral anticoagulation can reduce stroke risk in AF patients; however, medication non-adherence can eliminate this benefit. To date, reported patient adherence rates to oral anticoagulation regimens vary. The objective of the current study was to examine the impact of medication-specific education delivered via a personal health record (PHR) system on medication adherence. A randomized, prospective study was conducted from February 2014 to June 2014 at Parkview Health, a not-for-profit, community-based health care clinic that serves a northeastern Indiana population of more than 820,000. AF patients receiving dabigatran (Pradaxa s ; Boehringer Ingelheim GmbH, Ingelheim am Rhein, Germany) to prevent stroke participated in this study. The study participants were predominantly Caucasian males over 65 years of age who were educated, insured, and living above the poverty level. Patients were allowed to view online, download, and transmit health information via a PHR. The intervention group received PHR training and dabigatran education via the PHR. The control group received standard care and PHR access without training. A longitudinal survey pertaining to medication knowledge, medication adherence, and patient engagement was administered at baseline and at the end of the study. Medication-dispensing data collected from pharmacy refill prescriptions were used for calculating the medication possession ratio (MPR). Ninety patients were included in this study, and were randomly assigned to either the intervention group (n ¼ 46) or the control group (n ¼ 44). All participants completed the baseline survey, and 95.6% of patients finished the follow-up survey. The mean score for knowledge increased significantly in the intervention group (from 3.77 to 4.23, p ¼ 0.005), but not in the control group (from 3.70 to 3.95, p ¼ 0.72). The MPR was significantly higher in the intervention group (97.47% vs. 87.67%, p ¼ 0.001). Both groups had similar levels of improvement in Patient Activation Measure scores (from 63.0 to 65.8, p ¼ 0.078 vs. from 63.1 to 63.6, p ¼ 0.814). Patients who used the PHR achieved greater medication knowledge, resulting in improved medication adherence. To our knowledge, no published randomized trial has reported on the use of PHRs to improve medication adherence and knowledge. This study is the first to demonstrate a positive impact on anticoagulation adherence with PHR use.

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Section: Health Information Technologymentioning

confidence: 99%

The Use of Electronic Personal Health Records to Improve Medication Adherence and Patient Engagement: A Randomized Study of Non-valvular Atrial Fibrillation Patients

Chen¹,

Roebuck²,

Sami³

et al. 2017

J Innov Cardiac Rhythm Manage

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“…O comportamento de não-adesão ao tratamento medicamentoso é achado frequente em diversas doenças, sobretudo naquelas de natureza crônica e, provavelmente, constitui a causa mais importante de insucesso terapêutico (6) . Na DC, a complexidade de determinado tratamento que inclui regimes terapêuticos que necessitam a ingestão diária de vários comprimidos com diferentes horários de administração, seja durante a atividade ou a remissão da doença, pode influenciar negativamente o grau de adesão do paciente (18,37) . Também o acesso aos medicamentos utilizados no tratamento da DC pode ser dificultado ou mesmo impedido em função do alto custo destas drogas.…”

Section: Introductionunclassified

Não-adesão ao tratamento em pacientes com doença de Crohn: prevalência e fatores de risco

Cornélio

Pinto

Pace

et al. 2009

Arq. Gastroenterol.

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RESUMO -Contexto -A não-adesão ao tratamento medicamentoso, em algum grau, ocorre universalmente. É uma das principais causas de insucesso no tratamento das doenças crônicas, tal como a doença de Crohn. Objetivo -Em doentes com doença de Crohn, avaliar a prevalência e os fatores de risco associados à baixa adesão ao tratamento medicamentoso. Resultados -Entre os pacientes avaliados, 64% apresentaram escore compatível com não-adesão. O perfil mais frequente de não-adesão foi o do tipo não-intencional, e os pacientes mostraram ter conhecimento e motivação para o tratamento. Na comparação entre os dois grupos observou-se somente uma tendência a não-adesão entre os pacientes mais jovens (P = 0,07) e de raça não-branca (P = 0,06). Não houve correlação significativa entre o grau de adesão e as variáveis psicológicas e farmacoterapêuticas. Conclusões -Em pacientes com doença de Crohn, a prevalência de não-adesão ao tratamento medicamentoso é elevada (64%). Indivíduos jovens e aqueles não-brancos parecem ser os mais predispostos à não-adesão. Portanto, é preciso estar alerta para sua ocorrência e, caso necessário, implementar medidas que busquem aumentar o grau de adesão destes pacientes. DESCRITORES -Doença de Crohn. Recusa do paciente ao tratamento. Esquema de medicação. INTRODUÇÃOA doença de Crohn (DC) é uma afecção crônica de natureza sistêmica que pode afetar qualquer segmento do sistema digestório (22) . Tipicamente, sua história natural é marcada por períodos de atividade e remissão (34) . No mundo, diversos estudos têm demonstrado aumento significativo de sua incidência, principalmente na segunda metade do século XX (10,31) . No Brasil, alguns estudos demonstraram tendência semelhante (11,35) . O tratamento da DC visa induzir ou manter sua remissão, evitar ou reduzir as complicações e melhorar a qualidade de vida dos pacientes afetados (11) . Na maioria dos pacientes existe necessidade de tratamento medicamentoso prolongado e, muitas vezes, por tempo indeterminado. O atual arsenal terapêutico inclui o uso de aminossalicilatos, antibióticos, glicocorticóides sistêmicos e não-sistêmicos, imunomoduladores e anticorpos monoclonais anti-fator de necrose tumoral (TNF) alfa (27) . O comportamento de não-adesão ao tratamento medicamentoso é achado frequente em diversas doenças, sobretudo naquelas de natureza crônica e, provavelmente, constitui a causa mais importante de insucesso terapêutico (6) . Na DC, a complexidade de determinado tratamento que inclui regimes terapêuticos que necessitam a ingestão diária de vários comprimidos com diferentes horários de administração, seja durante a atividade ou a remissão da doença, pode influenciar negativamente o grau de adesão do paciente (18,37) . Também o acesso aos medicamentos utilizados no tratamento da DC pode ser dificultado ou mesmo impedido em função do alto custo destas drogas. Tal fato é apontado como preditor de não-adesão (9) ; entretanto, um estudo demonstrou que o fornecimento gratuito de medicamentos ao paciente não garante adesão adequada (8) . Além disso, fatore...

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“…Previous studies had confirmed that lack of understanding or adherence importance denial characterizes non-adherent patients, and is a significant factor with negative impact on the degree of adherence to prescriptions in patients with chronic diseases (Vlasnik et al, 2005;Al-Qasem et al, 2011).…”

Section: Results and Their Discussionmentioning

confidence: 94%

Proceedings of the Iii International Scientific and Practical Conference “Psychological Health of the Person: Life Resource and Life Potential”

2017

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The Proceedings cover different aspects of mental health research concerned with human life resource and life potential, as well as applied aspects of health psychology.The editorial policy was based on the principles of selection and reviewing of all submitted manuscripts. At the first stage all the manuscripts underwent an initial review by the Editor-in-Chief and the Editorial Board before peer-review in order to assess whether their content complied with the Conference theme. The manuscripts which did not comply with the subject matter of the Conference have been rejected. At the second stage all the manuscripts underwent a double blind review process: each work was reviewed by two experts from the Board of Reviewers; reviewing procedure was anonymous both for the experts and authors.In case of positive review results provided by both experts the contributions were included in the Editor-in-Chief Portfolio. At the third stage manuscripts underwent scientific style as well as language literacy assessment and language editing. This work was carried out by the team of Language Editors. Based on the results of the three stages of reviewing the list of the manuscripts recommended for the publication in the Conference Proceedings has been defined.The problem of assessment, prophylaxis and preserving human psychological health is of utmost importance today. Its relevance is determined, first, by the fact that both a person and his / her development as a healthy and autonomous personality represent a subject of a psychological research. Second, recent global transformations impose special requirements to the person seeking for health preservation, self-development, and self-actualisation. Among these requirements there is readiness to act in new, unpredictable conditions, to make decisions in unstable situations and to bear responsibility for one's decisions. To meet these requirements, a person should be able to see opportunities for self-development and self-fulfillment in the surrounding world, finding new meanings of his / her life activity.Existence of life resource and life potential expands the scope of any person's activities, turning the person's significant life purposes into more achievable ones. Resources are known to subjectively increase the value of a person both in his / her self-perception and in the eyes of others, making the person stronger, more prominent and proactive.Among various human resources health is a fundamental one. At the same time, life potential is not a less important characteristic, since it ensures human capacity to create, develop and use life conditions, factors and circumstances which are beneficial for an organism.Considering human health through the prism of life potential, it is necessary that the value of health within culture of its formation should be the highest, being defined not so much by the need for self-preservation but for self-improvement.The presented Proceedings are the result of both scientific studies in Psychology and fruitful and prospective long-term inte...

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Medication adherence: Factors influencing compliance with prescribed medication plans

Cited by 129 publications

References 40 publications

The Use of Electronic Personal Health Records to Improve Medication Adherence and Patient Engagement: A Randomized Study of Non-valvular Atrial Fibrillation Patients

The Use of Electronic Personal Health Records to Improve Medication Adherence and Patient Engagement: A Randomized Study of Non-valvular Atrial Fibrillation Patients

Não-adesão ao tratamento em pacientes com doença de Crohn: prevalência e fatores de risco

Proceedings of the Iii International Scientific and Practical Conference “Psychological Health of the Person: Life Resource and Life Potential”

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