Medication Adherence During Pregnancy in IBD: Compliance Avoids Complications

Gaidos, Jill; Kane, Sunanda V.

doi:10.1007/s10620-020-06271-w

Cited by 2 publications

(1 citation statement)

References 9 publications

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“…Most IBD medications are deemed low-risk during pregnancy [57]. As mentioned, it's crucial to have the disease well-controlled during pregnancy since IBD flare-ups during this period can increase the risk of obstetric complications.…”

Section: Treatments and Pregnancymentioning

confidence: 99%

IBD and Motherhood: A Journey through Conception, Pregnancy and Beyond

Caballero-Mateos,

Quesada-Caballero,

Cañadas-De la Fuente

et al. 2023

JCM

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Inflammatory Bowel Disease (IBD) presents distinct challenges during pregnancy due to its influence on maternal health and pregnancy outcomes. This literature review aims to dissect the existing scientific evidence on pregnancy in women with IBD and provide evidence-based recommendations for clinical management. A comprehensive search was conducted across scientific databases, selecting clinical studies, systematic reviews, and other pertinent resources. Numerous studies have underscored an increased risk of complications during pregnancy for women with IBD, including preterm birth, low birth weight, neonates small for gestational age, and congenital malformations. Nevertheless, it’s evident that proactive disease management before and throughout pregnancy can mitigate these risks. Continuation of IBD treatment during pregnancy and breastfeeding is deemed safe with agents like thiopurines, anti-TNF, vedolizumab, or ustekinumab. However, there’s a call for caution when combining treatments due to the heightened risk of severe infections in the first year of life. For small molecules, their use is advised against in both scenarios. Effective disease management, minimizing disease activity, and interdisciplinary care are pivotal in attending to women with IBD. The emphasis is placed on the continual assessment of maternal and infant outcomes and an expressed need for further research to enhance the understanding of the ties between IBD and adverse pregnancy outcomes.

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Section: Treatments and Pregnancymentioning

confidence: 99%

IBD and Motherhood: A Journey through Conception, Pregnancy and Beyond

Caballero-Mateos,

Quesada-Caballero,

Cañadas-De la Fuente

et al. 2023

JCM

View full text Add to dashboard Cite

show abstract

IBD and Motherhood: A Journey Through Conception, Pregnancy, and Beyond.

Caballero-Mateos,

Quesada-Caballero,

Cañadas-De la Fuente

et al. 2023

Preprint

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Inflammatory Bowel Disease (IBD) presents distinct challenges during pregnancy due to its influence on maternal health and pregnancy outcomes. This literature review aims to dissect the existing scientific evidence on pregnancy in women with IBD and provide evidence-based recommendations for clinical management. A comprehensive search was conducted across scientific databases, selecting clinical studies, systematic reviews, and other pertinent resources. Numerous studies have underscored an increased risk of complications during pregnancy for women with IBD, including preterm birth, low birth weight, neonates small for gestational age, and congenital malformations. Nevertheless, it's evident that proactive disease management before and throughout pregnancy can mitigate these risks. Continuation of IBD treatment during pregnancy and breastfeeding is deemed safe with agents like thiopurines, anti-TNF, vedolizumab, or ustekinumab. However, there's a call for caution when combining treatments due to the heightened risk of severe infections in the first year of life. For small molecules, their use is advised against in both scenarios. Effective disease management, minimizing disease activity, and interdisciplinary care are pivotal in attending to women with IBD. The emphasis is placed on the continual assessment of maternal and infant outcomes and an expressed need for further research to enhance the understanding of the ties between IBD and adverse pregnancy outcomes.

show abstract

Medication Adherence During Pregnancy in IBD: Compliance Avoids Complications

Abstract: Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Cited by 2 publications

References 9 publications

IBD and Motherhood: A Journey through Conception, Pregnancy and Beyond

IBD and Motherhood: A Journey through Conception, Pregnancy and Beyond

IBD and Motherhood: A Journey Through Conception, Pregnancy, and Beyond.

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