Medication Adherence Contributes to an Improved Quality of Life in Type 2 Diabetes Mellitus Patients: A Cross-Sectional Study

Alfian, Sofa D.; Sukandar, Hadyana; Lestari, Keri; Abdulah, Rizky

doi:10.1007/s13300-016-0203-x

Cited by 63 publications

(67 citation statements)

References 34 publications

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“…However, the findings remain controversial. Consistent with our findings, several studies have previously demonstrated the beneficial effects of medication adherence on improved QoL in epileptic patients [10,44,45] and other diseases [46,47]. Loon et al [47] found that adherence to glaucoma medications was associated with better QoL.…”

Section: Discussionsupporting

confidence: 92%

Health-related quality of life and medication adherence in elderly patients with epilepsy

Hamedi−Shahraki

Eshraghian

Yekaninejad

et al. 2019

Neurol Neurochir Pol.

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Objective. Considering the high prevalence of epilepsy in the elderly and the importance of maximising their quality of life (QoL), this study aimed to investigate the relationship between medication adherence and QoL, and the mediating effects of medication adherence on the association between serum antiepileptic drug (AED) level and seizure severity with QoL in elderly epileptics. Methods. In a longitudinal study, 766 elderly patients with epilepsy who were prescribed a minimum of one antiepileptic drug were selected by convenience sampling method. A Medication Adherence Report Scale (MARS-5) questionnaire was completed at the baseline. Seizure severity and QoL were assessed after six months using the Liverpool Seizure Severity Scale (LSSS) and the QoL in Epilepsy (QOLIE-31) questionnaires respectively. Serum level of AED was also measured at six-month follow-up. Results. Medication adherence was significantly correlated with both seizure severity (β =-0.33, p < 0.0001) and serum AED level (β = 0.29, p < 0.0001) after adjusting for demographic and clinical characteristics. Neither QoL nor its sub-classes were correlated with seizure severity. In addition, a significant correlation was not observed between serum AED level and QoL. However, medication adherence was significantly correlated with QoL (β = 0.30, p < 0.0001). The mediating effects of medication adherence on the association between serum AED level (Z = 3.39, p < 0.001) and seizure severity (Z =-3.47, p < 0.001) with QoL were supported by the Sobel test. Conclusion. This study demonstrates that medication adherence has a beneficial impact on QoL in elderly epileptics. Therefore, adherence to treatment should be monitored to improve their QoL.

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Section: Discussionsupporting

confidence: 92%

Health-related quality of life and medication adherence in elderly patients with epilepsy

Hamedi−Shahraki

Eshraghian

Yekaninejad

et al. 2019

Neurol Neurochir Pol.

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“…Therefore, due to chronic nature of the disease, the likelihood of non-adherence is expected [23]. Adherence to the prescribed medication was positively linked with diabetes-specific -quality of life in patients [24].…”

Section: Disscussion Adherence To Medicationmentioning

confidence: 99%

Adherence to Oral Antidiabetic Medications among Type 2 Diabetic (T2DM) Patients in Chronic Ambulatory Wards of Hiwot Fana Specialized University Hospital, Harar, Eastern Ethiopia: A Cross Sectional Study

Jemal¹,

Abdela²,

Sisay³

2017

J Diabetes Metab

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Background: Diabetes mellitus (DM) refers to a group of common metabolic disorders that share the characteristic of hyperglycemia. It is associated with abnormalities in carbohydrate, fat, and protein metabolism and results in chronic complications including microvascular, macrovascular, and neuropathic disorders. Evidence indicates that it is the level of blood glucose, which the patients can achieve during their treatment, influences diabetic complications on the long run. Achievement of optimal blood sugar level is generally based appropriate utilization of existing oral antidiabetic drugs, proper adherence to prescribed regimens and patients' own managements of their illness. The study was, therefore, aimed to assess adherence to oral antidiabetic drugs among diabetic patients attending chronic ambulatory wards of Hiwot Fana Specialized University Hospital (HFSUH).

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“…The BIPQ assesses eight dimensions, i.e., consequences, timeline, personal control, treatment control, identity, concern, coherence and emotional response. The higher score of BIPQ domains, the more negative perception of patients (question number 1, 2, 5,6,8). On the other dimensions (i.e., personal control, treatment control and coherence) the higher the score, the more positive the perceptions of the patients are (number 3, 4, and 7).…”

Section: Methodsmentioning

confidence: 99%

Illness Perceptions and Quality of Life in Patients with Diabetes Mellitus Type 2

Perwitasari

Santosa

Faridah

et al. 2017

Indones J Clin Pharm

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One of the treatment objectives in patients with type 2 diabetes mellitus (T2DM) is improving their quality of life (QoL). Illness perceptions are major determinant of QOL. This study was aimed to evaluate the QoL of T2DM patients with complications, and to examine the correlation between patients' illness perceptions and QoL. We conducted a cross-sectional study in a private hospital in Yogyakarta, Indonesia from July to September 2015. We recruited adult patients with a diagnosis of T2DM with complications (ICD E.11) that has been diagnosed for at least 3 months. Illness perceptions were assessed with the Brief Illness Perception Questionnaire (BIPQ), and diabetes type 2 specific QoL with the Diabetes Quality of Life for Clinical Trial Questionnaire (DQLCTQ). Data was analyzed using Pearson correlation test. We recruited 51 T2DM patients. Female patients were dominant and most of the subjects experienced T2DM more than 5 years. The BIPQ scores indicated that patients had positive perceptions about T2DM and the treatment in all domains, except for coherence. Scores on the DQLCTQ showed that T2DM patients' QoL is good, except for the self satisfaction and treatment effect. Statistically significant positive correlations were observed between BIPQ dimensions of personal control, treatment control and coherence and QoL domains (p<0.01). Moreover, the strong negative correlation were observed between consequences, concern and emotional response and QoL domains (p<0.01). However, 92% correlations are weak. Illness perceptions are correlated with T2DM patients' QoL. Interventions aimed to get more adaptive illness perceptions may impact positively on QoL.Keywords: BIPQ, DQLCTQ, illness perceptions, Indonesia, QoL, T2DM Persepsi terhadap Penyakit dan Kualitas Hidup Pasien Diabetes Melitus Tipe 2 AbstrakSalah satu tujuan terapi DM tipe 2 adalah memperbaiki kualitas hidup pasien. Persepsi terhadap penyakit merupakan penentu utama dari kualitas hidup. Tujuan penelitian ini adalah untuk mengevaluasi kualitas hidup pasien pada pasien DM tipe 2 dengan komplikasi serta mengetahui hubungan antara persepsi pasien dan kualitas hidup. Rancangan penelitian ini adalah potong lintang yang dilakukan di rumah sakit swasta di Yogyakarta. Subyek yang berpartisipasi dalam penelitian ini adalah pasien DM tipe 2 dewasa dengan komplikasi yang terdiagnosa minimal 3 bulan sebelum penelitian ini dimulai (ICD E11). Kualitas hidup diukur dengan Diabetes Quality of Life for Clinical Trial Questionnaire (DQLCTQ) dan persepsi pasien diukur dengan Brief Illness Perception Questionnaire (BIPQ). Sejumlah 51 pasien DM tipe 2 dengan komplikasi turut berpartisipasi dalam penelitian ini dari bulan Juli sampai September 2015. Mayoritas subjek adalah wanita dan sebagian besar pasien mengalami DM tipe 2 lebih dari 5 tahun. Skor domain BIPQ memperlihatkan bahwa pasien DM tipe 2 mempunyai persepsi yang positif terhadap penyakit dan pengobatannya pada semua domain kecuali koherensi. Skor domain DQLCTQ memperlihatkan bahwa pasien mempunyai kualitas hidu...

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Medication Adherence Contributes to an Improved Quality of Life in Type 2 Diabetes Mellitus Patients: A Cross-Sectional Study

Cited by 63 publications

References 34 publications

Health-related quality of life and medication adherence in elderly patients with epilepsy

Health-related quality of life and medication adherence in elderly patients with epilepsy

Adherence to Oral Antidiabetic Medications among Type 2 Diabetic (T2DM) Patients in Chronic Ambulatory Wards of Hiwot Fana Specialized University Hospital, Harar, Eastern Ethiopia: A Cross Sectional Study

Illness Perceptions and Quality of Life in Patients with Diabetes Mellitus Type 2

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