Medicated Manuka honey in conservative management of exomphalos major

Nicoara, Cezar Doru; Singh, Michael; Jester, Ingo; Reda, B; Parikh, Dakshesh

doi:10.1007/s00383-014-3490-1

Cited by 17 publications

(11 citation statements)

References 24 publications

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“…It has been observed that the effectiveness of natural commercial honey in combination with a hydroalginate and off-loading in managing diabetic foot ulcers is possible at primary care level [75]. Medicated monuka honey was found to be effective in treating exomphalos major [76].…”

Section: Wound Healing Property Of Honeymentioning

confidence: 99%

The anti-inflammatory and wound healing properties of honey

Hadagali

Chua

2014

Eur Food Res Technol

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Section: Wound Healing Property Of Honeymentioning

confidence: 99%

The anti-inflammatory and wound healing properties of honey

Hadagali

Chua

2014

Eur Food Res Technol

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“…The most widely used honeys in medicine are Manuka ( Leptospermum scoparium ) honey and Revamil ® source (RS) honey that have varying degrees of antimicrobial activity towards different pathogens . Manuka honey has been shown to be effective in the healing of surgical wounds . Manuka honey contains the antimicrobial agent methylglyoxyl (MGO), which has been reported to originate from dihydroxyacetone of the Manuka flower as well as a number of unidentified metabolites, proteins and peptides.…”

Section: Introductionmentioning

confidence: 99%

A pilot study investigating lactic acid bacterial symbionts from the honeybee in inhibiting human chronic wound pathogens

Butler

Öien²,

Lindholm

et al. 2014

International Wound Journal

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Treatment and management of chronic wounds is a large burden on the health sector and causes substantial suffering for the patients. We believe that 13 lactic acid bacteria (LAB) symbionts isolated from the honey crop of the honeybee are important players in the antimicrobial action of honey, by producing antimicrobial substances and can be used in combination with heather honey as an effective treatment in wound management. A total of 22 patients with chronic ulcers were included; culture-dependent and molecular-based (MALDI-MS and 16S rRNA gene sequencing) techniques were used to identify bacteria from chronic wounds. These clinical isolates were used for in vitro antimicrobial testing with standardised viable LAB and sterilised heather honey mixture. Twenty of the patients' wounds were polymicrobial and 42 different species were isolated. Patient isolates that were tested in vitro were inhibited by the LAB and honey combination with inhibitory zones comparable with different antibiotics. LAB and heather honey in combination presents a new topical option in chronic wound management because of the healing properties of honey, antimicrobial metabolite production from the LAB and their bactericidal effect on common chronic wound pathogens. This new treatment may be a stepping stone towards an alternative solution to antibiotics.

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“…4 Many chemicals are known to do so and have been used, for example, mercurochrome, povidone iodine, 5,6 alcohol, silver sulpha diazine, 7 silver nitrate, gentian violet, 8 aqueous eosin 9 and Manuka honey. 10 Silastic sheet application has also been done to encourage granulation underneath it. 11 When epithelisation of the sac has been achieved a ventral hernia is created which is closed in a second stage surgery.…”

Section: Discussionmentioning

confidence: 99%