Medically assisted nutrition for adult palliative care patients

Good, Phillip; Richard, Russell; Syrmis, William; Jenkins-Marsh, Sue; Stephens, Jane

doi:10.1002/14651858.cd006274.pub3

Cited by 51 publications

(55 citation statements)

References 14 publications

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“…Concerning the nutritional approach, the single reported study 24 seems to show an advantage in its use, even if the Cochrane review 5 and the available guidelines 3,26 seem to exclude a real advantage for parenteral nutrition in the refractory phase of cancer cachexia.…”

Section: Discussionmentioning

confidence: 99%

“…4 A Cochrane Systematic Review on the use of medically assisted nutrition in palliative care patients concludes that There are insufficient good quality studies to make any recommendations for practice. 5 Therefore, according to a recent position paper, 6 the decision to administer parenteral nutrition should be tailored to individual patients on a clinical basis and should be consistent with the goals of patient care.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Treatment of cancer cachexia in the very advanced or terminal phase: a systematic review

Arvia¹,

Giordani²,

Ghaderi³

et al. 2013

Ital J Med

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The therapeutic approach to refractory cancer cachexia represents an unmet need and an important research priority in the field of palliative care. Unfortunately, clinical studies in this area are scarce, both regarding nutritional and pharmacological approach. We performed a systematic literature search through Pubmed. The search algorithm considered: the clinical context, the related pathology, the therapeutic approach. The abstracts obtained were entered in a spreadsheet and analyzed in full text. The results were then analyzed according to the PRISMA method. Overall, 258 records were screened: 244 were excluded (not in English, n=44; no abstract, n=12; literature reviews, n=108; not relevant for not advanced phase or phase II studies, n=80). The remaining 14 papers were read in full text: 10 were excluded (4 phase II studies, 4 including patients with a performance status score of ≥70%, 2 including patients concomitantly treated by palliative chemotherapy). The remaining 4 studies of qualitative synthesis included: a study on megestrol acetate; a comparison between supportive treatment with/without melatonin; a placebo-controlled study on intravenous adenosine 5'-triphosphate; a comparison of indomethacin plus erythropoietin with/without nutritional support. The reported data do not allow us to draw any conclusion concerning the efficacy of pharmacological or nutritional treatment for cancer cachexia in very advanced or terminal phase and specific studies are, therefore, awaited.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Treatment of cancer cachexia in the very advanced or terminal phase: a systematic review

Arvia¹,

Giordani²,

Ghaderi³

et al. 2013

Ital J Med

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“…However, in this study, the median period of hospitalization was significantly shorter for gastrostomy-fed patients than for nasogastric tube-fed patients (21 vs. 64 days). Although artificial nutrition in terminally ill cancer patients is controversial (24,25), this difference might reflect the fact that patients with a PEG tube were able to receive nutrition and medications as long as possible before hospitalization. In other words, patients without a PEG tube may have been hospitalized earlier due to malnutrition than patients with a PEG tube.…”

Section: Discussionmentioning

confidence: 99%

Quality of life and functional status of terminally ill head and neck cancer patients: a nation-wide, prospective observational study at tertiary cancer centers in Japan

Shinozaki

Ebihara²,

Iwase

et al. 2016

Jpn. J. Clin. Oncol.

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Background: Little is known about quality of life and functional status of patients with terminally ill head and neck cancers. Methods: We conducted a multicenter, prospective, observational study to examine quality of life and functional status in terminally ill head and neck cancer patients. Results: Of the 100 patients meeting inclusion criteria, 72 were observed until death. There was no significant difference in the quality of life score between baseline and Week 3. Forty patients (54.9%) could speak and 22 patients (30.5%) could have oral intake upon study entry. Fifty-three patients (74.6%) received enteral nutrition. Twenty-six patients (36.6%) required dressing changes for fungating tumors. The route of nutritional intake (nasogastric tube vs. percutaneous gastric tube) might be predictive for the duration of hospital stay (64 vs. 21 days, P = 0.0372). Conclusion: There was no significant relationship between quality of life and functional status seen in this study. Feeding tube type could have the most impact on quality of life.

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“…Ein Cochrane Review aus dem Jahr 2014 bemängelte das Vorliegen qualitativ hochwertiger Studien, sodass bis dato keine wirkliche Praxisempfehlung ausgesprochen werden kann [22]. Eine orale Nahrungszufuhr stellt nach wie vor die physiologischste Art der Kalorienzufuhr dar, wobei zu betonen ist, dass eine künstliche Ernährung keinen tumorstimulierenden Effekt hat.…”

Section: Therapieunclassified

Palliativmedizin: Grundlagen und Symptommanagement

Masel

Watzke

2017

Wien. Klin. Wochenschr. Educ

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Medically assisted nutrition for adult palliative care patients

Cited by 51 publications

References 14 publications

Treatment of cancer cachexia in the very advanced or terminal phase: a systematic review

Treatment of cancer cachexia in the very advanced or terminal phase: a systematic review

Quality of life and functional status of terminally ill head and neck cancer patients: a nation-wide, prospective observational study at tertiary cancer centers in Japan

Palliativmedizin: Grundlagen und Symptommanagement

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