Medical treatment of an unusual cerebral hydatid disease

Chen, Shu; Li, Ning; Yang, Feifei; Wu, Jiqin; Hu, Yuekai; Yu, Shudong; Chen, Qi; Wang, Xuan; Wang, Xinyu; Liu, Yuanyuan; Zheng, Jianming

doi:10.1186/s12879-017-2935-2

Cited by 19 publications

(29 citation statements)

References 11 publications

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“…Cerebral HC, a rare disease, doesn't exceed 2 % of the cases and is more frequent in children and young adults, representing 50 to 70% of the cases. However, all ages can be affected (5,6). We noted 2 cases of cerebral HC, which were both among children.…”

Section: Discussionmentioning

confidence: 72%

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Hydatid disease among adults and children: it is time to worry!

et al. 2019

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Background: Hydatid disease is a public health issue as it continues to produce substantial morbidity and mortality. The most common affected organ among adults is the liver and among children, is the lungs. Its treatment includes medical therapy, surgical intervention or percutaneous drainage. We aimed to identify the clinical, therapeutic and evolutionary features of hydatid cyst among adults and children. Method: We conducted a retrospective study including all patients hospitalized in Pediatric and Infectious disease department for hydatid cyst between 1990 and 2018. Results: Overall, we enrolled 71 patients, among whom 37 (52.1%) were male. The median age was 28 years [3-87years]. The revealing symptoms were fever in 19 cases (26.7%) and cough in 18 cases (25.3%). Hepatic hydatid cyst was the main site, noted in 45 cases (63.4%), among which adults represented 37 cases (52.1%). Hydatid serology was positive in 87.2% of the cases. The treatment was surgical and followed by medical treatment based on albendazole in 43 cases (60.5%). The median duration of treatment was 4 months [1-60 months]. The most common adverse reactions of albendazole were elevated hepatic enzymes and reversible alopecia noted in 7 (12.7%) and 5 cases (9%). The disease evolution was marked by the occurrence of recovery in 53 cases (74.7%). Conclusion: Our study highlighted the burden of hydatid disease in our region, which remains endemic. It might be misdiagnosed since not only clinical symptoms are misleading, but also, imaging results can be concealing.

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Section: Discussionmentioning

confidence: 72%

“…Therefore, effective treatment includes both chemotherapy and surgery. Otherwise, medical therapy is the only choice in inoperative forms or multifocal hydatidosis (6).…”

Section: Discussionmentioning

confidence: 99%

Hydatid disease among adults and children: it is time to worry!

et al. 2019

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“…In the present case, we have used a total dose of 400mg twice daily and intend to continue for a period of 6 months as per the available literature. 9,11…”

Section: Discussionmentioning

confidence: 99%

Giant Intracerebral Hydatid Cyst in a Boy

Thapa¹,

Tandon²,

Agrawal³

2020

Nep J Neurosci

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Giant intra-cerebral hydatid cysts are an extremely rare condition caused by the infestation of larvae of Taenia echinococcus (TE). Humans are infected through the feco-oral route by the ingestion of food and milk, contaminated by dog feces containing the ova of parasite or direct contact with dogs. We report a case of a seventeen-year-old boy with giant right temporo-parieto-occipital hydatid cysts (HC). Giant intracerebral hydatid cysts being rare and can at times lead to death, so surgical excision with preoperative consideration and intraoperative rupture prevention is the best management for a better prognosis.

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“…Therapeutically, surgical excision of the cyst represents the route of intake in recharge, associated with albendazole to avoid recovery of the lesion [11,12]. An assessment is required at 9 months, 12 months and 2 years.…”

Section: Discussionmentioning

confidence: 99%

Cerebral Hydatitosis: About 12 Observations at the University Hospital Center of Conakry

Cisse¹,

Sakadi²,

Sakho³

et al. 2018

CNN

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Cosmopolitan disease, hydatidosis is caused by the hydatid larvae of a tapeworm of Echinococcus granulosus canes developing in the liver, lungs, heart and central nervous system. The biological certainty of brain damage in West Africa is difficult to confirm because of the supposed rarity of this affection and the difficulties of accessibility to MRI and CT radiological data suggestive of the disease. We retrospectively analyzed the file of 268 patients hospitalized in the Neurology Department between 2010 and 2016 for the management of encephalic syndrome with cystic neuroradiological cerebral lesions. Biological and neuroradiological evidence of hydatidosis was reported in 12 patients (4, 47%). An encephalic and infectious syndrome: headache, nausea and vomiting, fever, disorders of consciousness, sensitivo-motor deficit with hemiparesis type, cerebellar syndrome and sometimes visual disorders, expression of intracranial hypertension was found in patients. These elements of intracranial hypertension objectified in most patients, were associated in 3 cases with liver disorders. The biological data haemagglutination, Eliza, moderate eosinophilia, radiological CT / MRI and the demonstration of scolex during percutaneous aspirations (2 cases) and on operative specimens were the diagnostic confirmation beam.

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Medical treatment of an unusual cerebral hydatid disease

Cited by 19 publications

References 11 publications

Hydatid disease among adults and children: it is time to worry!

Hydatid disease among adults and children: it is time to worry!

Giant Intracerebral Hydatid Cyst in a Boy

Cerebral Hydatitosis: About 12 Observations at the University Hospital Center of Conakry

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