Medical toxicology in the Old Testament. The poisonous pottage

Mazokopakis, Elias E.; Karagiannis, Christos

doi:10.1111/imj.13641

Cited by 6 publications

(5 citation statements)

References 10 publications

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“…The ingestion of this fruit, however, may have many undesired effects. The biblical story of non-fatal accidental poisoning (described in The Book of 2 Kings) is a related report of the medical toxicology of C. colocynthis in the Old Testament [87]. Feeding a mixture of Nerium oleander and C. colocynthis caused more marked effects and the death of rats [21].…”

Section: Toxicitymentioning

confidence: 99%

Citrullus colocynthis (L.) Schrad.: A Promising Pharmaceutical Resource for Multiple Diseases

Cheng,

Qin,

Chen

et al. 2023

Molecules

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Citrullus colocynthis (L.) Schrad. (Cucurbitaceae) is widely distributed in the desert areas of the world. The fruit bodies of C. colocynthis are recognized for their wide range of nutraceutical potential, as well as medicinal and pharmaceutical uses. The plant has been reported for various uses, such as asthma, bronchitis, cancer, colic, common cold, cough, diabetes, dysentery, and jaundice. The fruit has been extensively studied for its biological activities, which include insecticide, antitumor, and antidiabetic effects. Numerous bioactive compounds have been reported in its fruit bodies, such as essential oils, fatty acids, glycosides, alkaloids, and flavonoids. Of these, flavonoids or caffeic acid derivatives are the constituents associated with the inhibition of fungal or bacterial growth, whereas eudesmane sesquiterpenes or sesquiterpene lactones are most active against insects, mites, and nematodes. In this review, the scientific evidence for the biological activity of C. colocynthis against insecticide, cytotoxic, and antidiabetic effects is summarized.

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Section: Toxicitymentioning

confidence: 99%

Citrullus colocynthis (L.) Schrad.: A Promising Pharmaceutical Resource for Multiple Diseases

Cheng,

Qin,

Chen

et al. 2023

Molecules

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“…We read with interest the recent paper by Mazokopakis and Karagiannis considering toxicological candidates for the poisoning of the prophets’ sons recounted in 2 Kings 4: 38–41. Here, we propose an underlying mechanism that we argue may be relevant to several celebrated biblical maladies.…”

mentioning

confidence: 99%

Biblical myoglobinuria

Benhamou

Sultan²,

Warren

2018

Internal Medicine Journal

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“…We refer to the article ‘Medical toxicology in the Old Testament. The poisonous pottage’ by Mazokopakis and Karagiannis . We were interested to find that specific knowledge of the treatment of herb poisoning existed in antiquity and that readily available household items could be used for the treatment of such poisoning.…”

mentioning

confidence: 99%