Medical Therapy of Glaucoma

Meta-analysis of randomised controlled trials comparing latanoprost with brimonidine in the treatment of open-angle glaucoma, ocular hypertension or normal-tension glaucoma

“…Despite this, IOPR is the mainstay of treatment. 2 Several studies have shown this to reduce the progression of optic nerve damage and visual field loss in patients with increased IOP [28][29][30] or NTG. 31…”

“…1 Despite advances in laser and surgical treatments, lowering of intraocular pressure (IOP) with topical drugs remains the initial treatment of choice for most patients. 2 The prostaglandin analogues and a 2 -agonists are two common classes of topical antiglaucomatous treatments that are being increasingly prescribed. 3 Latanoprost (Xalatan; Pharmacia, Peapack, New Jersey, USA) is a prodrug of a prostaglandin F 2a analogue that increases aqueous outflow predominantly through the uveoscleral pathway.…”