Medical, Psychological and Intellectual Development of 5-Year-Old Children Born after Intracytoplasmic Sperm Injection

Abstract

Once severe congenital anomalies were excluded, there were no differences in physical and neurodevelopmental outcome of 5-year-old ICSI children compared with controls.With regard to behaviour and emotional development, ICSI children seem to be similar or might be even more stable and socially competent than the control children. As our study is limited by the small sample size, further research is needed to confirm our results.

Childhood growth of singletons conceived following in vitro fertilisation or intracytoplasmic sperm injection: a systematic review and meta‐analysis

“…The age of the children in these studies ranged from 1.5 to 6.4 years. The majority of the studies did not show any association between conception following IVF or ICSI and childhood weight and height; however, a few studies found larger height in childhood among children exposed to IVF compared with spontaneously conceived controls. Miles et al.…”

“…A total of seven of the included 20 studies did not report child weight and/or height in means and standard deviations in the published paper or upon request to the author . The age of the children in these studies ranged from 1.5 to 6.4 years.…”

“…Thus, we were able to include 13 studies in the meta‐analyses. The remaining seven studies were included as a narrative review and are described below …”

“…The remaining seven studies were included as a narrative review and are described below. [8][9][10][11][29][30][31]…”

“…A total of seven of the included 20 studies did not report child weight and/or height in means and standard deviations in the published paper or upon request to the author. [8][9][10][11][29][30][31] The age of the children in these studies ranged from 1.5 to 6.4 years. The majority of the studies did not show any association between conception following IVF or ICSI and childhood weight and height; 8,[29][30][31] however, a few studies found larger height in childhood among children exposed to IVF compared with spontaneously conceived controls.…”