Medical Pearl: Confirming the diagnosis of molluscum contagiosum using 10% potassium hydroxide

Bauer, Jacob H.; Miller, O. Fred; Peckham, Steven J.

doi:10.1016/j.jaad.2006.08.045

Cited by 11 publications

(3 citation statements)

References 5 publications

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“…In addition to Giemsa, other staining techniques such as Wright, 10% potassium hydroxide, Gram and Papanicolaou have been described in literature. 5,6,7,8 …”

Section: Discussionmentioning

confidence: 99%

Diagnosis of Atypical Molluscum Contagiosum: The Utility of a Squash Preparation

Eleftheriou

Kerr²,

Stratman³

2010

Clinical Medicine & Research

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A 4-year-old boy was referred to the outpatient dermatology clinic for two growths on his scalp. The first lesion had been present on the vertex scalp for six months and was asymptomatic except for recent inflammation and drainage of white exudate. A second growth developed on the patient's posterior parietal scalp in recent weeks and reportedly resembled the original appearance of the initial lesion. Review of systems was negative, and the parents denied any affected close contacts. There had been no intervention to the lesions. On examination, the vertex of the scalp revealed a 0.3 cm hemorrhagic crusted papule with surrounding desquamation and minimal surrounding erythema. The left posterior parietal scalp had a 0.2 cm

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“…In addition to Giemsa, other staining techniques such as Wright, 10% potassium hydroxide, Gram and Papanicolaou have been described in literature. 5,6,7,8 …”

Section: Discussionmentioning

confidence: 99%

Diagnosis of Atypical Molluscum Contagiosum: The Utility of a Squash Preparation

Eleftheriou

Kerr²,

Stratman³

2010

Clinical Medicine & Research

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“…Diagnosis can be done rapidly by electron microscopy (6) . A quick and reliable in-clinic method to confirm the diagnosis of MC using 10% KOH solution which is added to crushed material of the core of MC, keratin will sufficiently clear within minutes, and the clustered, round or oval-shaped Henderson Paterson bodies are easily seen within the specimen (10) .…”

Section: Diagnosismentioning

confidence: 99%

Molluscum Contagiusum in AL Najaf City Patients and Its Relationship to handshaking and kissing: An Epidemiological Study

Abdullah¹,

Raheem²

2020

kjns

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Background: Molluscum Contagiusum is a common viral infection of the skin, caused by a poxvirus, commonly affects young children. The disease is common, although the incidence in most areas is not reliably known. An infection transmitted through contact with infected persons or contaminated objects. Aim of the study: To study the relationship between the transmission mechanisms of molluscum contagiusum with handshaking and kissing. Methodology: This study was conducted in the Department of Dermatology and Venereology-Al-Sadir Medical City in Al-Najaf from March \ 2016 to January \ 2017. Ninety-five patients were included in this study. Full history and physical examination were done for all patients. The age of patients, sex, number of lesions, site of distribution, duration of lesions and family history were assessed. Results: Ninety-five patients with molluscum contagiusum 72(54.3%) males and 23(45.6%) females with a male to female ratio 1.19-1. Their ages ranged from 1.5-62 years (mean and standard deviation 19.4+16.7). The disease duration varies between 1-24 weeks with a mean ± SD of 5.17± 4.407 weeks. The most common affected body sites are the face and most of the lesions appear on the right side of the face. Conclusion: It is clear from the results in this study that the right side of the face is the most infected side. This indicates that there is direct contact with lesion mostly related to handshaking and kissing. Recommendations: we recommend to study involves larger number of the patients as and to check the relationship to other actions like swimming. ___________________________________________________________________________________ *M.D., Dermatologist, department of dermatologist, faculty of medicine, university of Kufa.

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“…Diagnosis can be carried out rapidly by electron microscopy [15]. A quick and reliable in-clinic method to confirm the diagnosis of MC using 10% KOH solution which is added to crushed material of the core of MC, keratin will sufficiently clear within minutes, and the clustered, round or oval shaped Henderson Paterson bodies are easily seen within the specimen [26].…”

Section: Diagnosismentioning

confidence: 99%

Treatment of Molluscum Contagiosum by Potassium Hydroxide Solution 20% with and Without Pricking and By Pricking Alone: A Comparative Study with Review of Literature

Maluki¹

2015

Int J Dermatol Clin Res

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Background: Molluscum Contagiosum is a common viral skin infection, caused by poxvirus, commonly affects young children. Although there is no specific treatment for this infection, many therapeutic modalities has been used with different success rates. Objectives: To evaluate the effectiveness of topical 20% KOH, 20% KOH with pricking and pricking alone as comparative treatments for molluscum contagiosum. Patients and methods: This study was conducted in the Dermatology Clinic of Kufa Medical School Teaching Hospital in Iraq, from August 2011 to January 2013. Ninety patients with Molluscum Contagiosum were recruited. Diagnosis of Molluscum Contagiosum was confirmed on clinical bases. Patients with prior treatment for the last month and patients who had inflamed lesions were excluded. Full history and physical examination were done for all Patients. The patients were divided into three groups: Group 1included 30 patients treated with topical KOH 20% applied by wooden stick daily at bed time. Group 2 included 30 patients treated by pricking the lesions by 27 G needle wet in 20% KOH weekly. Group 3 included 30 patients treated by pricking alone once weekly. Treatment sessions were continued until complete cure or maximum of four sessions was achieved. The patients were followed up for two months period from the last session. Results: Out of the ninety patients, 57 completed the study. There were thirty one (54.3%) males and 26 (45.6%) females with male to female ratio 1.19-. Their ages ranged from 1.5-62 years (mean and standard deviation of 19.4±16.7). The most common age group affected was below 12 years, 29 (50.8%) patients. The most commonly affected body sites were the face and neck, 49 (85.9%) patients. After 4 sessions, the response rate was as follows:-Group 1, 17 (94.4%): patients were cured completely and relapse was not recorded; p-value was highly significant (=0.0019).-Group 2, 20 (86.4%) patients were completely cured and relapse was not recorded; p-value was highly significant (< 0.001).-Group 3, 12 (75%) patients were completely cured and relapse was not recorded; p-value was highly significant (=0.0014). Conclusion: Pricking Molluscum Contagiosum by 27G needle alone, pricking with 20% KOH and topically applied 20% KOH all achieved comparable success rates that were all statistically significant. All three methods represented tolerable and highly effective modes of therapy. Historical review: MC was first described and later assigned its name by Bateman in the beginning of the Nineteenth Century. In 1841, Henderson and Paterson described the intracytoplasmic inclusion bodies now known as Molluscum or Henderson-Paterson bodies. In the early Twentieth Century, Julinsberg, Wile and Kingery were able to extract filterable virus from lesions and show transmissibility. Goodpasture later described the similarities of Molluscum and vaccinia [2].

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Medical Pearl: Confirming the diagnosis of molluscum contagiosum using 10% potassium hydroxide

Cited by 11 publications

References 5 publications

Diagnosis of Atypical Molluscum Contagiosum: The Utility of a Squash Preparation

Diagnosis of Atypical Molluscum Contagiosum: The Utility of a Squash Preparation

Molluscum Contagiusum in AL Najaf City Patients and Its Relationship to handshaking and kissing: An Epidemiological Study

Treatment of Molluscum Contagiosum by Potassium Hydroxide Solution 20% with and Without Pricking and By Pricking Alone: A Comparative Study with Review of Literature

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