Medical marijuana use for pediatric oncology patients: single institution experience

Ofir, Ruth; Bar-Sela, Gil; Ben‐Arush, Myriam Weyl; Postovsky, Sergey

doi:10.1080/08880018.2019.1630537

Cited by 13 publications

(34 citation statements)

References 19 publications

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“…Regarding the symptom clusters evaluated in the five included studies, the oncological pain was verified to be the most evaluated symptom by four studies (43)(44)(45)(46) , followed by the symptom nausea, evaluated by three studies (42,(44)(45) . The symptoms loss of appetite (42,45) and anxiety (43)(44) were also evaluated by two studies, respectively. Cancer-related fatigue was evaluated by a single study (42) , as was the symptom sleep disorder (45) .…”

Section: Characteristics Of Study Interventionsmentioning

confidence: 99%

“…Regarding the characteristics of the five included studies, the date of publication was verified to range from 2000 to 2020 (42)(43)(44)(45)(46) , all of them were published in English in four different countries (Germany, Canada, United States, and Israel), and had a quasi-experimental design. Chart 2 synthesizes chronologically the main characteristics of the studies included in the qualitative synthesis.…”

Section: Study Characterizationmentioning

confidence: 99%

“…Chart 2 synthesizes chronologically the main characteristics of the studies included in the qualitative synthesis. was quality of life, analyzed in two studies (45)(46) . Regarding the time of follow-up, all studies presented a short period, with intervention protocols varying among the studies (42)(43)(44)(45)(46) .…”

Section: Study Characterizationmentioning

confidence: 99%

“…The instruments used to evaluate the symptom clusters in children and adolescents with cancer undergoing palliative care, only one study was verified not to use validated instruments to measure such symptom groups, using subjective analysis through the oncologists' observation (42) . The most often reported instruments were VAS (43,45) , FACES (43)(44) , and FLACC (44)(45) .…”

Section: Study Characterizationmentioning

confidence: 99%

“…The total of research participants in the studies (42)(43)(44)(45)(46) included in this systematic review was 146 patients, and samples varied from 6 months to 19 years of age (mean age of 10 years and a half ). With regards to the use of complementary therapies in the included studies, two were verified to use therapeutic massage (44,46) , one used reiki (43) ; one study used boswellic acid (42) and another one (45) evaluated the use of Cannabis sativa (marijuana) for the management of symptom clusters in children and adolescents with cancer undergoing palliative care.…”

Section: Characteristics Of Study Interventionsmentioning

confidence: 99%

See 4 more Smart Citations

Effectiveness of complementary therapies for the management of symptom clusters in palliative care in pediatric oncology: a systematic review

Lopes-Júnior

Urbano

Schuab

et al. 2021

Rev. esc. enferm. USP

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Objective: To evaluate the effectiveness of complementary therapies in the management of symptom clusters in children and adolescents with cancer undergoing palliative care. Method: Systematic review guided by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses, resorting to the databases MEDLINE, Web of Science, Central Cochrane, and PsycINFO. The identification, selection, inclusion, extraction, and methodological assessment were conducted by two independent reviewers. Results: Five quasi-experiments met the eligibility criteria. The heterogeneous characteristics of the studies made meta-analysis impossible. Two studies used therapeutic massage, one used Reiki, one used boswellic acid, and one used Cannabis sativa; three of them (therapeutic massage and Reiki) presented statistically significant results for the management of the cluster pain-anxiety-worry-dyspnea. Most studies presented a moderate risk of bias as per ROBINS-I tool. Conclusion: Therapeutic massage and Reiki may be effective for the symptom clusters management, especially the pain-anxiety-worry-dyspnea cluster in children and adolescents undergoing palliative care.

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Section: Characteristics Of Study Interventionsmentioning

confidence: 99%

Section: Study Characterizationmentioning

confidence: 99%

Section: Study Characterizationmentioning

confidence: 99%

Section: Study Characterizationmentioning

confidence: 99%

Section: Characteristics Of Study Interventionsmentioning

confidence: 99%

See 3 more Smart Citations

Effectiveness of complementary therapies for the management of symptom clusters in palliative care in pediatric oncology: a systematic review

Lopes-Júnior

Urbano

Schuab

et al. 2021

Rev. esc. enferm. USP

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Cannabinoids for symptom management in children with cancer: A systematic review and meta‐analysis

Chhabra,

Ben‐Eltriki,

Paul

et al. 2023

Cancer

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BackgroundDespite the widespread use of medical cannabis, little is known regarding the safety, efficacy, and dosing of cannabis products in children with cancer. The objective of this study was to systematically appraise the existing published literature for the use of cannabis products in children with cancer.MethodsThis systematic review, registered with the International Prospective Register of Systematic Reviews (CRD42020187433), searched four databases: MEDLINE, Embase, PsycINFO, and the Cochrane Library. Abstracts and full texts were screened in duplicate. Data on types of cannabis products, doses, formulations, frequencies, routes of administration, indications, and clinical and demographic details as well as reported efficacy outcomes were extracted. Data on cannabinoid‐related adverse events were also summarized.ResultsOut of 34,611 identified citations, 19 unique studies with a total of 1927 participants with cancer were included: eight retrospective chart reviews, seven randomized controlled trials, two open‐label studies, and two case reports. The included studies reported the use of various cannabis products for the management of symptoms. Cannabinoids were commonly used for the management of chemotherapy‐induced nausea and vomiting (11 of 19 [58%]). In controlled studies, somnolence, dizziness, dry mouth, and withdrawal due to adverse events were more commonly associated with the use of cannabinoids. Across all included studies, no serious cannabis‐related adverse events were reported.ConclusionsAlthough there is evidence to support the use of cannabis for symptom management, in children with cancer, there is a lack of rigorous evidence to inform the dosing, safety, and efficacy of cannabinoids. Because of the increasing interest in using cannabis, there is an urgent need for more research on medical cannabis in children with cancer.

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Cannabinoids for symptom management in children with cancer: It’s complicated

Spraker‐Perlman,

Heidelberg

2023

Cancer

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Medical marijuana use for pediatric oncology patients: single institution experience

Cited by 13 publications

References 19 publications

Effectiveness of complementary therapies for the management of symptom clusters in palliative care in pediatric oncology: a systematic review

Effectiveness of complementary therapies for the management of symptom clusters in palliative care in pediatric oncology: a systematic review

Cannabinoids for symptom management in children with cancer: A systematic review and meta‐analysis

Cannabinoids for symptom management in children with cancer: It’s complicated

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