Medical management of oral submucous fibrosis

Abstract

<p class="abstract"><strong>Background:</strong> <span lang="EN-IN">In 1952 Schwartz coined the term “atrophica idiopathica mucosa oris” to describe an oral fibrosing disease he discovered in 5 Indian women from Kenya. Oral submucous fibrosis of oral cavity is a chronic progressive debilitating disease and premalignant condition of oral cavity. The condition is well recognized for its malignant potential and it is particularly associated with aracanut chewing. It is characterized by burning sensation in mouth particularly while eating spicy food and progressive development of inability to open mouth. Worldwide estimate of oral submucous fibrosis indicate that 2.5 million people are affected with a higher incidence in Indian subcontinent. </span></p><p class="abstract"><strong>Methods:</strong> <span lang="EN-IN">This is an observational type of study of 100 patients with oral submucous fibrosis attending ENT OPD. </span></p><p class="abstract"><strong>Results:</strong> <span lang="EN-IN">We observed that with effective combination of treatment and avoiding predisposing factors and with long time follow-up we got markedly good results. </span></p><p class="abstract"><strong>Conclusions:</strong> <span lang="EN-IN">Although medical management does not completely cure the disease but optimal doses of injection corticosteroid with injection hyaluronidase with avoidance of predisposing factors and improvement of dietary habit with prolong follow up is effective in some extent.</span></p>

Efficacy of Curcumin in Combination with Intralesional Dexamethasone with Hyaluronidase in the Treatment of Oral Submucous Fibrosis: A Randomized Controlled Trial

“…Also, in the study by Das et al, (2012), patients receiving curcumin capsules and those receiving turmeric oil showed a statistically significant increase in mouth opening (Das et al, 2012). However, Agrawal et al, (2017), showed no significant improvement in mouth opening with low dose of curcumin (Agrawal et al, 2017). The mean improvement in tongue protrusion at first visit and 6 weeks follow-up was higher in Group A compared to that in Group B.…”

Patterns and predictors of periodontal disease and tooth loss among users of smokeless tobacco

“…Tobacco chewing habit also results in gingival recession, halitosis, gingival irritation, oral mucosal ulcers and sores [ 13 ]. Oral ulceration caused by SLT results in difficulty to consume spicy foods [ 14 ]. Weakening senses of smell and taste are also noticed [ 15 ].…”