Rare side-effects of f1uoroquinolone therapy are tendinitis and tendon rupture. Many reports have demonstrated that the concomitant use of corticosteroids, in patients aged 60 years or older, increase the risk substantially. We present a case of spontaneous bilateral Achilles tendon rupture induced by ciprofloxacin and methylprednisolone. A 61-year-old woman was diagnosed with Bronchiolitis Obliterans with Organizing Pneumonia (BOOP) and was started on oral ciprofloxacin 500 mg twice daily for 3 weeks and on oral methylprednisolone 16 mg twice daily for 2 weeks. The diagnosis was made after doctors, rather than stop drug therapy and advise complete rest, had mistakenly prescribed for the woman to undergo physiotherapy and local NSAIDs, thus favoring the onset of tendon ruptures and resulting in surgical and legal implications. Inspired by this case, we also submit a brief review on professional liability in Orthopaedics.Fluoroquinolones (FQs) represent a major class of antimicrobials that have a high potential as therapeutic agents. The newer generation agents have been demonstrated to be effective in the treatment of upper and lower respiratory tract infections. Although FQs (as ciprofloxacin and levofloxcin) are generally safe for use as antimicrobials, they may induce tendinopathic complications such as tendinitis and tendon rupture (1-4).Severalfactorshave suggestedto predisposea patient ..to tendoninjury:age over 60 years,renalfailure,diabetes mellitus, renal transplantation, hyperparathyroidism, rheumatic disease, trauma and corticosteroidtreatment.In particular,the concomitant use ofcorticosteroidsand fluoroquinolones in elderly patients increasesthe risk of Achilles tendon rupture (5-6). In fact, many reports (5, 7) have shown that oral corticosteroid use was not only an important independent risk factor but, in combination with current exposure to quinolones, it also strongly increased the risk of Achilles tendon rupture in patients over 60 years of age.We present a case ofspontaneous bilateral Achilles tendon rupture which occurred in a 61-year-old woman following ciprofloxacin and methylprednisolone administration for the treatment of Bronchiolitis Obliterans with Organizing Pneumonia (BOOP).
CaseReportA 61-year-old woman was diagnosed with