Medical Grade Calcium Sulfate Hemihydrate in Healing of Human Extraction Sockets: Clinical and Histological Observations at 3 Months

Abstract

MGCSH seems to be an ideal graft material in extraction socket bone regeneration because it is almost completely resorbable, and it allows a new trabecular bone arrangement at 3 months.

Ridge preservation comparing a flap vs. a flapless technique using a demineralized bone matrix allograft plus mineralized particulate allograft and covered with a calcium sulfate barrier.

“…They reported 67% vital bone and 33% trabecular space. These results compare well to the results seen by Vance et al (2004) with DFDBA and the calcium sulfate putty (CaIMatrix®) and Guarnieri et al (2004) with the medical grade calcium sulfate.…”

“…Alloplastic materials such as bioactive glass, hydroxyapatite (RA) and calcium sulfate have shown percentage vital bone around 35-60% (MacNeill et al 1999, Froum et al 2002and Guarnieri et al 2004. Alloplasts are well tolerated by the host and have been shown to be osteoconductive in nature, but not osteoinductive.…”

“…Alloplasts are well tolerated by the host and have been shown to be osteoconductive in nature, but not osteoinductive. Guarnieri et al (2004) in a 10 socket study utilizing medical grade calcium sulfate hemi-hydrate in extraction sockets and found at 3 months that 100% of the graft had been resorbed and that there was 58% vital bone present throughout the preservation site. The site was also devoid of any inflammatory cells and connective tissue.…”

Sulfato de calcio: propiedades y aplicaciones clínicas

“…Cambios dimensionales Post-extracción fueron similares en ambos grupos, pero fue significativamente hueso más vitales en el grupo putty de masilla experimental (61%) frente al grupo xenoinjerto (26%) (31) . Otros clínicos (32,33) , han informado de resultados positivos cuando han utilizado sulfato de calcio como un material para la preservación del reborde en forma de relleno y de barrera en procedimientos de postextracción, proporciona una barrera que estabiliza el coágulo y excluye a los tejidos no deseados (por ejemplo, tejido epitelial, gingival y conectivo). Ayudando a cicatrizar y regenerar la zona para la colocación del implante adecuado, eliminando cualquier necesidad de posteriores injertos en bloque, o alguna otra forma de aumento del reborde, proporcionando un ahorro tanto para el paciente en tiempo y dinero.…”

Ridge preservation comparing the clinical and histologic healing of a mineralized particulate allograft with a nonporous PTFE membrane vs. mineralized particulate xenograft with a collagen plug membrane.

“…Alloplastic materials such as bioactive glass, hydroxyapatite (RA) and calcium sulfate have been shown to have vital bone from 2S to 60% (MacNeill et al 1999, Froum et al 2002, 2004Guarnieri et al 2004, and Mangano et al 2008. Alloplasts are well tolerated by the host and tend to be osteoconductive in nature rather than osteoinductive.…”