Medical gloves modified by a one-minute spraying process with blood-repellent, antibacterial and wound-healing abilities

Zhuo, Yi; Cheng, Xinyan; Fang, Hua; Wang, Bing; Jia, Shuang; Li, Weihao; Yang, Xuetao; Zhang, Yan; Wang, Xiaolei

doi:10.1039/d1bm01212f

Cited by 5 publications

(10 citation statements)

References 40 publications

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“…Zhuo et al. [ 125 ] proposed superhydrophobic blood‐repellent mist spray coating that could be sprayed on the surface of ordinary medical gloves to obtain blood‐repellent gloves. As shown in Figure 8c, blood adhesion can appear on the surface of ordinary gloves when operating.…”

Section: Application Of Sbfrssmentioning

confidence: 99%

“…In addition to improving the anti‐thrombotic properties of medical instruments (catheters, blood bags), extracorporeal medical protective equipment, such as surgical gloves and gowns, also need blood‐repellent properties. [ 56,125 ] Given bleeding during an operation is almost inevitable, gloves become sticky after being in contact with blood, which reduces the quality and may increase the difficulty of the operation. Additionally, sticky blood or body fluids transfer micro‐organisms between surgeon and patients.…”

Section: Application Of Sbfrssmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Superhydrophobic Biological Fluid‐Repellent Surfaces: Mechanisms and Applications

Luo

et al. 2022

Small Methods

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Superhydrophobic biological fluid‐repellent surfaces (SBFRSs) have attracted great attention in the treatment of blood and urine‐related diseases because of their unique wettability and compatibility, which creates a new path for the development of medical apparatus and instruments, and are expected to create advances in various fields. Here, this review provides an up‐to‐date summary of research progress on the repellent mechanism and application of SBFRSs. The underlying physical and chemical principles for designing superhydrophobic surfaces are first introduced. Then, the dialectical influences of solid‐liquid interactions between superhydrophobic surfaces and biological fluids on the wettability and compatibility are emphatically expounded. Subsequently, attention is drawn to the recent applications of SBFRSs in biomedical fields, such as surgical medical apparatus, implant materials, extracorporeal circulation devices, and biological fluid detection. Finally, the outlook and challenges in terms of employing SBFRSs are also discussed. This review is expected to provide a comprehensive guidance for the preparation of SBFRSs with compatibility and long‐term superhydrophobic stability that is closely related to clinical applications.

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Section: Application Of Sbfrssmentioning

confidence: 99%

Section: Application Of Sbfrssmentioning

confidence: 99%

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Superhydrophobic Biological Fluid‐Repellent Surfaces: Mechanisms and Applications

Luo

et al. 2022

Small Methods

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“…Recently, the hemocompatibility of superhydrophobic materials or coatings has been brought to attention because they can significantly reduce the contact area of blood with the material and reduce the adhesion force, enhancing blood compatibility by reducing the available binding sites for protein adsorption or platelet adhesion. 25,26 Meanwhile, the antifouling properties of the superhydrophobic surface also prevent the infection of surgical devices by reducing the adhesion of bacteria and other organic substances. 27,28 Additionally, a superhydrophobic coating can prevent corrosion by not allowing the metal surface to come in contact with corrosive media.…”

Section: ■ Introductionmentioning

confidence: 99%

Biological Influence and Clinical Applications of the Unique Flower Shape of ZnO–ZnS@SA Superhydrophobic Composite Films Grown on Nanorods

Zhang

Pei

Weng

et al. 2023

ACS Sustainable Chem. Eng.

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Surgical devices inevitably come into contact with blood, bacteria, high temperatures, high humidity, and acidic, basic, and salt environments during use, which can have a significant impact on the device and the operator, so their protection becomes necessary. In this manuscript, novel, highly robust, and superhydrophobic Ni-doped ZnO–ZnS@stearic acid (SA) composite films with extreme repellency to various solid and liquid contaminants, excellent bactericidal performance, and extremely low blood adhesion were fabricated by a simple one-step hydrothermal method. Additionally, the synergistic effect of the in situ generated hierarchical micro/nanocomposite structures on the Zn substrate surface and SA also endowed the film with excellent mechanical and chemical stability, such as ultra-low adhesion, perfect wear resistance, corrosion resistance, heat resistance, and good durability. Notably, the superhydrophobic composite films could be turned into a superhydrophilic film by simple heat treatment. Further, it could revert to its superhydrophobic state by remodification of stearic acid. This unique structure and low surface energy SA modification were found to be the primary reasons for the excellent protection and versatility of galvanized surgical devices in various extreme environments.

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“…Due to the nonwetting behavior of superhydrophobic surfaces, many methods have been used to prepare the superhydrophobic surface to resist bacterial adhesion and blood contamination, such as spraying, thermal oxidation, deposition, hydrothermal method, and so on. − The fact is each preparation method has its advantages around different research objectives (such as controlling material morphology, hydrophilicity, adhesion, stability, etc. ). , For example, Zhang prepared a novel superhydrophobic surface with a hierarchical architecture and bimetallic composition by a facile galvanic replacement reaction, followed by a simple thermal oxidation process, which showed excellent antibacterial activity under various working conditions.…”

Section: Introductionmentioning

confidence: 99%

Construction of Hierarchical Micro/Nanostructured ZnO/Cu–ZnMOFs@SA Superhydrophobic Composite Coatings with Excellent Multifunctionality of Anticorrosion, Blood-Repelling, and Antimicrobial Properties

Zhang

Pei

Huang

et al. 2022

ACS Appl. Mater. Interfaces

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Naked medical devices are often damaged by blood, bacteria, and other extreme environmental conditions (heat, humidity, acid, alkali, salts, and others), causing device failure and increasing difficulty for the operator. They can also cause inflammation and coagulation resulting in severe complications and even death. In this work, the superhydrophobic ZnO/copper−zinc metal−organic frameworks@stearic acid (ZnO/Cu−ZnMOFs@SA) composite coatings with hierarchical micro/nanostructures were fabricated on Zn substrates via a one-step hydrothermal method. The effects of hierarchical micro/nanostructures on surface wettability, physicochemical stability, and biological properties have been studied in this manuscript. The structure not only provided the coatings with robust waterproofing, abrasive resistance, durability, and thermal and light irradiation stability but also successfully recovered their superhydrophobicity by remodifying the surface with SA, showing excellent repeatability. In addition, the coating demonstrates excellent corrosion resistance and self-cleaning ability and rejects various solid and liquid contaminants. The superhydrophobic ZnO/Cu−ZnMOFs@SA composite coatings also exhibited excellent antibacterial and thrombosis resistance. The findings indicated that the superhydrophobic composite coatings have a strong potential for application in medical instruments for exhibiting multifunctional properties in various extreme environments.

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Medical gloves modified by a one-minute spraying process with blood-repellent, antibacterial and wound-healing abilities

Abstract: A kind of blood-repellent mist spray (MS) was proposed to prevent blood adhesion during surgery and played an important role in antibacterial and wound-healing, which could be widely used in the surface modification of various medical gloves.

Cited by 5 publications

References 40 publications

Superhydrophobic Biological Fluid‐Repellent Surfaces: Mechanisms and Applications

Superhydrophobic Biological Fluid‐Repellent Surfaces: Mechanisms and Applications

Biological Influence and Clinical Applications of the Unique Flower Shape of ZnO–ZnS@SA Superhydrophobic Composite Films Grown on Nanorods

Construction of Hierarchical Micro/Nanostructured ZnO/Cu–ZnMOFs@SA Superhydrophobic Composite Coatings with Excellent Multifunctionality of Anticorrosion, Blood-Repelling, and Antimicrobial Properties

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