Medical and Dental Implications of Down Syndrome: A Review Part 1: General and Craniofacial Characteristic

Ghaith, Batool; Kowash, Mawlood; El-Halabi, Manal

doi:10.2174/2213476x03666160901125732

Cited by 2 publications

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“…1 People with Down Syndrome are more prone to suffer from orofacial conditions such as dental anomalies, malocclusion, periodontal disease, xerostomia, a compromised buffer capacity of saliva, and soft tissue disturbances such as inverted lips and protruding tongues. 2,4,5 They have dysfunctional chewing and swallowing, a higher probability of being mouth breathers, and they are also susceptible to demineralization and dental caries. 6 Uncooperative behavior during dental care, poor oral health, and susceptibility to periodontal disease make people with Down Syndrome at an increased risk for poor oral health.…”

Section: Introductionmentioning

confidence: 99%

Management of Chronic Ulcer Mimicking Oral Squamous Cell Carcinoma in Down Syndrome Child with Motoric Disorders

Shafuria¹,

Dwiarie²,

Hidayat³

2022

IMCRJ

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Introduction Down syndrome is a congenital genetic disorder caused by an error in cell division, resulting in the presence of an additional third chromosome 21. Down syndrome is one of the leading causes of intellectual disability. Millions of these patients face various health issues. This study aimed to provide information about the challenges in the management of chronic ulcer mimicking OSCC in Down Syndrome child with motoric disorders. Case A 12-year-old boy with Down Syndrome and motoric disorders was referred to Oral Medicine Department. In the extraoral examination, the patient had a dysmorphic face and dry lips. Lymph node examination could not be assessed because the patient wore a cervical collar. The intraoral examination showed an irregular ulcer with 1×0.7 cm in diameter, indurated margin, and white-yellowish base at the right lateral border of the tongue. The 55 teeth were sharp and caused an occlusion trauma to the right lateral border of the tongue. The patient was diagnosed with a chronic traumatic ulcer mimicking OSCC based on clinical examination. The medication given to the patient were sodium chloride 0.9%, povidone-iodine mouthwash 1%, and petroleum jelly. Conclusion Children with Down syndrome often suffer from orofacial abnormalities which can affect their oral health and their family’s quality of life. Dental and oral care for Down Syndrome children with motoric disorders required some challenges and collaboration with their parents, families, and caregivers.

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Section: Introductionmentioning

confidence: 99%

Management of Chronic Ulcer Mimicking Oral Squamous Cell Carcinoma in Down Syndrome Child with Motoric Disorders

Shafuria¹,

Dwiarie²,

Hidayat³

2022

IMCRJ

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Comparison of oral indices in patients with Down syndrome and healthy individuals: A meta-analysis study

Nilchian,

Mosayebi,

Tarrahi

et al. 2023

Dental Research Journal

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Background: The aim of the present study was to compare dental indexes of pediatric Down syndrome (DS) patients to those who are healthy. Materials and Methods: This study was carried out based on Preferred Reporting Items for Systematic Reviews and Meta-Analysis statement guidelines. The researchers searched title and abstract of major databases, including ProQuest (ProQuest Dissertations and Theses Full Text: Health and Medicine, ProQuest Nursing and Allie Health Source), PubMed, Google Scholar, clinical key, up to date, springer, Cochrane, Scopus, Embase, and Web of Science (ISI), up to September 2020 with restriction to English and Persian language This meta-analysis study had three outcomes: decay/miss/filled index, plaque index, and gingival index. Effect size, including mean difference and its 95% of confidence interval, was calculated. The Newcastle–Ottawa Scale measured the quality of the selected studies. Heterogeneity was performed using the Q test and I 2 index, and reporting bias was assessed using a funnel plot and Egger and Begg’s tests. Results: Fifteen studies conducted were included in the meta-analysis process. Conclusion: It showed that DS patients had a higher plaque index and gingival index than healthy individuals, which means that the oral health status of these patients is worse and needs more attention.

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Medical and Dental Implications of Down Syndrome: A Review Part 1: General and Craniofacial Characteristic

Cited by 2 publications

References 0 publications

Management of Chronic Ulcer Mimicking Oral Squamous Cell Carcinoma in Down Syndrome Child with Motoric Disorders

Management of Chronic Ulcer Mimicking Oral Squamous Cell Carcinoma in Down Syndrome Child with Motoric Disorders

Comparison of oral indices in patients with Down syndrome and healthy individuals: A meta-analysis study

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