Medical 3D Printing Using Desktop Inverted Vat Photopolymerization: Background, Clinical Applications, and Challenges

Patel, Parimal; Dhal, Kashish; Gupta, Ram P.; Tappa, Karthik; Rybicki, Frank J.; Ravi, Prashanth

doi:10.3390/bioengineering10070782

Cited by 13 publications

(8 citation statements)

References 116 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Despite the remarkable advancements, challenges persist in the field of AM in healthcare [33]. Issues such as insufficient mechanical properties in 3D printing, the imperative to scale up production for mass manufacturing, the development of intelligent printable biomaterials, and the intricate task of vascularization in 3D bioprinting pose ongoing hurdles [34][35][36][37][38].…”

Section: Discussionmentioning

confidence: 99%

Additive Manufacturing for Surgical Planning and Education: A Review

Kantaros,

Petrescu,

Abdoli

et al. 2024

Applied Sciences

View full text Add to dashboard Cite

Additive manufacturing has been widely used in various industries, including the healthcare sector. Over the last few decades, AM has been playing an important role in the medical field in different areas, including surgical planning, implants, and educational activities. For surgical applications, AM can help surgeons practice and plan an operation until they are confident with the process. This can help to reduce operational risk and time. In addition, it can help to demonstrate the problem to other colleagues. AM has also been used to produce 3D models to teach students and doctors about human anatomy. This paper aims to comprehensively review the diverse applications of additive manufacturing within the domains of surgical planning and medical education. By focusing on the multifaceted roles played by AM in these critical areas, a contribution to the growing body of knowledge that underscores the transformative potential of this technology in shaping the future of healthcare practices is sought to be made.

show abstract

Section: Discussionmentioning

confidence: 99%

Additive Manufacturing for Surgical Planning and Education: A Review

Kantaros,

Petrescu,

Abdoli

et al. 2024

Applied Sciences

View full text Add to dashboard Cite

show abstract

“…Additive manufacturing (AM) is defined as “a method based on adding materials layer upon layer to form 3D objects from 3D model data” by the American Society for Testing and Materials 2 . AM has found significant use in the medical field due to its capacity to control the addition of materials and customize complex geometries that cater to the specific requirements of individual patients with different conditions 3 , 4 . Some of the most common medical applications of AM include producing medical models, implants, and surgical instruments 4 .…”

Section: Introductionmentioning

confidence: 99%

“…Specifically, AM can obtain patient geometry through data acquisition methods such as CT scans, and rebuild real anatomical models. Not only does it provide surgeons with preoperative practice opportunities, but it can also be used to design patient-specific implants 3 . However, AM processing in medical applications can cause damage to mechanical properties, resulting in undesirable transformations and distortion 4 .…”

Section: Introductionmentioning

confidence: 99%

Effects of washing agents on the mechanical and biocompatibility properties of water-washable 3D printing crown and bridge resin

Liu,

Jin,

Lim

et al. 2024

Sci Rep

View full text Add to dashboard Cite

Three-dimensional (3D) printing, otherwise known as additive manufacturing in a non-technical context, is becoming increasingly popular in the field of dentistry. As an essential step in the 3D printing process, postwashing with organic solvents can damage the printed resin polymer and possibly pose a risk to human health. The development of water-washable dental resins means that water can be used as a washing agent. However, the effects of washing agents and washing times on the mechanical and biocompatibility properties of water-washable resins remain unclear. This study investigated the impact of different washing agents (water, detergent, and alcohol) and washing time points (5, 10, 20, and 30 min) on the flexural strength, Vickers hardness, surface characterization, degree of conversion, biocompatibility, and monomer elution of 3D printed samples. Using water for long-term washing better preserved the mechanical properties, caused a smooth surface, and improved the degree of conversion, with 20 min of washing with water achieving the same biological performance as organic solvents. Water is an applicable agent option for washing the 3D printing water-washable temporary crown and bridge resin in the postwashing process. This advancement facilitates the development of other water-washable intraoral resins and the optimization of clinical standard washing guidelines.

show abstract

“…SLA has an ink-dependent resolution, making it possible to create complex designs on the micron scale and emerging as a prominent CAD-CAM bio-fabrication method. Specifically, inverted SLA is used because of its ability to produce high-quality designs while having a smaller footprint and lower cost [26,27]. The flexibility of adding new design features printed using recently formulated biocompatible and sterilizable photoresins has increased the biomedical applications of this biofabrication method.…”

Section: Introductionmentioning

confidence: 99%

An Integrated Approach to Control the Penetration Depth of 3D-Printed Hollow Microneedles

Defelippi,

Kwong,

Appleget

et al. 2024

Applied Mechanics

View full text Add to dashboard Cite

A variety of hollow microneedle (HMN) designs has emerged for minimally invasive therapies and monitoring systems. In this study, a design change limiting the indentation depth of the (3D) printed custom microneedle assembly (circular array of five conical frusta with and without a stopper, aspect ratio = 1.875) fabricated using stereolithography has been experimentally validated and modeled in silico. The micro-indentation profiles generated in confined compression on 1 mm ± 0.073 mm alginate films enabled the generation of a Prony series, where displacement ranged from 100 to 250 µm. These constants were used as intrinsic properties simulating experimental ramp/release profiles. Puncture occurred on two distinct hydrogel formulations at the design depth of 150 µm and indentation rate of 0.1 mm/s characterized by a peak force of 3.5 N (H = 31 kPa) and 8.3 N (H = 36.5 kPa), respectively. Experimental and theoretical alignments for peak force trends were obtained when the printing resolution was simulated. Higher puncture force and uniformity inferred by the stopper was confirmed via microscopy and profilometry. Meanwhile, poroviscoelasticity characterization is required to distinguish mass loss vs. redistribution post-indentation through pycnometry. Results from this paper highlight the feasibility of insertion-depth control within the epidermis thickness for the first time in solid HMN literature.

show abstract

Medical 3D Printing Using Desktop Inverted Vat Photopolymerization: Background, Clinical Applications, and Challenges

Cited by 13 publications

References 116 publications

Additive Manufacturing for Surgical Planning and Education: A Review

Additive Manufacturing for Surgical Planning and Education: A Review

Effects of washing agents on the mechanical and biocompatibility properties of water-washable 3D printing crown and bridge resin

An Integrated Approach to Control the Penetration Depth of 3D-Printed Hollow Microneedles

Contact Info

Product

Resources

About