Medicaid healthcare expenditures for infants with birth defects potentially related to Zika virus infection in North Carolina, 2011–2016

Bergman, Kristin; Forestieri, Nina; Bona, Vito L. Di; Grosse, Scott D.; Moore, Cynthia A.

doi:10.1002/bdr2.1973

Cited by 3 publications

(1 citation statement)

References 24 publications

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“…27 Thus, our nding of multidomain developmental delays among children with ZBD is expected. Children with ZBD and neurodevelopmental sequelae require access to a broad range of specialized services and have high healthcare expenditures (median total expenditure per infant with defects of $30,544 for the rst year), particularly for public insurance programs in the U.S. 28 Understanding the prevalence of developmental delays and healthcare needs among children with CZVE (both those with and without ZBD) can inform health systems and planning to ensure there are services available for affected families.…”

Section: Discussionmentioning

confidence: 99%

Outcomes up to age 36 months after congenital Zika virus infection—U.S. states

Neelam,

Woodworth,

Chang

et al. 2023

Pediatr Res

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To characterize neurodevelopmental abnormalities in children up to 36 months of age with congenital Zika virus exposure. Methods:From the U.S. Zika Pregnancy and Infant Registry, a national surveillance system to monitor pregnancies with laboratory evidence of Zika virus infection, pregnancy outcomes and presence of Zika associated birth defects (ZBD) were reported among infants with available information. Neurologic sequelae and developmental delay were reported among children with ≥ 1 follow-up exam after 14 days of age or with ≥ 1 visit with development reported, respectively. Results:Among 2,248 infants, 10.1% were born preterm, and 10.5% were small-for-gestational age. Overall, 122 (5.4%) had any ZBD; 91.8% of infants had brain abnormalities or microcephaly, 23.0% had eye abnormalities, and 14.8% had both. Of 1,881 children ≥ 1 follow-up exam reported, neurologic sequelae were more common among children with ZBD (44.6%) vs. without ZBD (1.5%). Of children with ≥ 1 visit with development reported, 46.8% (51/109) of children with ZBD and 7.4% (129/1739) of children without ZBD had con rmed or possible developmental delay. Conclusion:Understanding the prevalence of developmental delays and healthcare needs of children with congenital Zika virus exposure can inform health systems and planning to ensure services are available for affected families.c The case de nition for Zika-associated birth defects (ZBDs) has been previously described 3,16

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Section: Discussionmentioning

confidence: 99%

Outcomes up to age 36 months after congenital Zika virus infection—U.S. states

Neelam,

Woodworth,

Chang

et al. 2023

Pediatr Res

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Outcomes Up to Age 36 Months after Congenital Zika Virus Infection – U.S. States

Neelam¹,

Woodworth²,

Chang

et al. 2023

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Background: To characterize neurodevelopmental abnormalities in children up to 36 months of age with congenital Zika virus exposure. Methods: From the U.S. Zika Pregnancy and Infant Registry, a national surveillance system to monitor pregnancies with laboratory evidence of Zika virus infection, pregnancy outcomes and presence of Zika associated birth defects (ZBD) were reported among infants with available information. Neurologic sequelae and developmental delay were reported among children with ≥ 1 follow-up exam after 14 days of age or with ≥ 1 visit with development reported, respectively. Results: Among 2,248 infants, 9.9% were born preterm, and 10.0% were small-for-gestational age. Overall, 122 (5.4%) had any ZBD; 91.8% of infants had brain abnormalities or microcephaly, 23.0% had eye abnormalities, and 14.8% had both. Of 1,881 children ≥ 1 follow-up exam reported, neurologic sequelae were more common among children with ZBD (44.6%) vs. without ZBD (1.5%). Of children with ≥ 1 visit with development reported, 46.8% (51/109) of children with ZBD and 7.4% (129/1739) of children without ZBD had confirmed or possible developmental delay. Conclusion: Understanding the prevalence of developmental delays and healthcare needs these children with congenital Zika virus exposure can inform health systems and planning to ensure services are available for affected families.

show abstract

Outcomes Up to Age 36 Months after Congenital Zika Virus Infection – U.S. States

Neelam¹,

Woodworth²,

Chang

et al. 2023

Preprint

Self Cite

View full text Add to dashboard Cite

Background: To characterize neurodevelopmental abnormalities in children up to 36 months of age with congenital Zika virus exposure. Methods: From the U.S. Zika Pregnancy and Infant Registry, a national surveillance system to monitor pregnancies with laboratory evidence of Zika virus infection, pregnancy outcomes and presence of Zika associated birth defects (ZBD) were reported among infants with available information. Neurologic sequelae and developmental delay were reported among children with ≥ 1 follow-up exam after 14 days of age or with ≥ 1 visit with development reported, respectively. Results: Among 2,248 infants, 10.1% were born preterm, and 10.5% were small-for-gestational age. Overall, 122 (5.4%) had any ZBD; 91.8% of infants had brain abnormalities or microcephaly, 23.0% had eye abnormalities, and 14.8% had both. Of 1,881 children ≥ 1 follow-up exam reported, neurologic sequelae were more common among children with ZBD (44.6%) vs. without ZBD (1.5%). Of children with ≥ 1 visit with development reported, 46.8% (51/109) of children with ZBD and 7.4% (129/1739) of children without ZBD had confirmed or possible developmental delay. Conclusion: Understanding the prevalence of developmental delays and healthcare needs of children with congenital Zika virus exposure can inform health systems and planning to ensure services are available for affected families.

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Medicaid healthcare expenditures for infants with birth defects potentially related to Zika virus infection in North Carolina, 2011–2016

Cited by 3 publications

References 24 publications

Outcomes up to age 36 months after congenital Zika virus infection—U.S. states

Outcomes up to age 36 months after congenital Zika virus infection—U.S. states

Outcomes Up to Age 36 Months after Congenital Zika Virus Infection – U.S. States

Outcomes Up to Age 36 Months after Congenital Zika Virus Infection – U.S. States

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