Mediastinum

Hecht, Silke

doi:10.1002/9781119533221.ch17

Cited by 1 publication

(2 citation statements)

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“…Ultrasonographic assessment of the spleen size is subjective. In dogs, the spleen margins appear round, and the organ extends caudally and to the right side of the abdomen [ 43 , 44 ]. Splenomegaly with normal echogenicity is found secondary to extramedullary haematopoiesis (including Babesia spp.…”

Section: Discussionmentioning

confidence: 99%

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Strategies for the Diagnosis of Granulocytic Anaplasmosis in Two Naturally Infected Dogs

Martinescu,

Ivănescu,

Ștefănescu

et al. 2023

Animals

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This study describes granulocytic anaplasmosis in two dogs naturally infected with Anaplasma phagocytophilum. The 3-year-old dogs (male and female) came from the same household and were referred to the Faculty of Veterinary Medicine in Iasi for blood donation. They were subject to standard routine tests: haematology blood test, blood smear, and serological tests (VETSCAN® FLEX4 and IDEXX SNAP 4Dx Plus). The female dog had no medical problems, while the male dog experienced joint pain. The blood smear was negative for tick-borne pathogens, and the haematology findings indicated thrombocytopenia in both dogs, with the male dog also displaying eosinophilia. The two dogs were mildly positive in the ELISA tests for the detection of Anaplasma spp. antibodies; therefore, the blood samples were tested using the qRT-PCR method for Anaplasma platys and Anaplasma phagocytophilum. The qRT-PCR result was negative for A. platys, but it was positive for A. phagocytophilum. The treatment consisted of the administration of doxycycline for 28 days. In conclusion, the high number of cases with non-specific clinical signs, the different sensitivity and specificity of the immunochromatographic serological tests, as well as the possibility of confusing the morula during the cytological examination, make the molecular test mandatory for precise diagnosis.

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Section: Discussionmentioning

confidence: 99%

“…infections and immune-mediated anaemia), infectious diseases, malignant infiltrations (lymphoma, mast cell tumours), splenic torsion, congestion, etc. [ 43 , 44 ].…”

Section: Discussionmentioning

confidence: 99%