Mediastinal schwannoma mimicking lymph node metastasis from locally advanced breast cancer in a 18 F-FDG PET/CT study

Martínez-Esteve, A.; Álvarez-Pérez, R.M.; Pachón-Garrudo, V.M.; González-Mancha, R.; Borrego-Dorado, I.

doi:10.1016/j.remn.2015.11.001

Cited by 2 publications

(3 citation statements)

References 3 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Mediastinal schwannomas can be misdiagnosed as lymph node metastasis [ 17 ]. The clinical distinction between mediastinal schwannoma and metastasis in cases where there is a history of cancer can be difficult, and requires surgical removal followed by histopathological analysis.…”

Section: Main Textmentioning

confidence: 99%

“…The location and composition obtained by means of imaging studies are critical to make a differential diagnosis. Even when using sophisticated studies, such a 18 F-fluorodeoxyglucose positron emission tomography and computed tomography ( 18 F-FDG PET/CT), mediastinal schwannomas can simulate metastases of breast cancer lymph nodes, as shown by Martinez-Esteve et al [ 17 ]. Similarly, we found a patient with a clinical history of stage IIB breast cancer during follow-up, which showed a mediastinal mass on a chest X-ray that was initially thought to be a recurrence of the disease.…”

Section: Main Textmentioning

confidence: 99%

See 1 more Smart Citation

Retrospective analysis of the clinical presentation and imaging of eight primary benign mediastinal schwannomas

et al. 2021

View full text Add to dashboard Cite

Objective Mediastinal schwannomas are sometimes confused with other neoplasms during initial radiological studies, especially when there is a history of cancer in another area. In these cases, a more accurate analysis using computed tomography (CT) or even magnetic resonance (MRI) is required. Our study aimed to perform a retrospective analysis of the clinical and imaging features for a series of patients with mediastinal schwannomas that were confirmed by histology and immunohistochemistry. Results We found eight patients, five men and three women, with an average age of 51 years for this study. The main signs and symptoms at diagnosis were chest pain, dyspnea, cough, and dysphagia. CT showed that the tumor was located in the posterior compartment of the chest in 7/8 cases. Tumors > 10 cm were more heterogeneous and showed cystic changes. All patients underwent posterolateral thoracotomy, and radiological follow-up showed no evidence of recurrence. Histological analysis was considered the gold standard to confirm diagnosis, along with at least one neurogenic IHC marker. In conclusion, mediastinal schwannomas are benign encapsulated tumors. According to CT, schwannomas > 10 cm show cystic degeneration more frequently. Posterolateral thoracotomy allows complete resection and is considered the surgical approach of choice.

show abstract

Section: Main Textmentioning

confidence: 99%

Section: Main Textmentioning

confidence: 99%

Retrospective analysis of the clinical presentation and imaging of eight primary benign mediastinal schwannomas

et al. 2021

View full text Add to dashboard Cite

show abstract

“…For example Martinez-Esteve et al ( 1 ) have reported the case of a patient with a locally advanced HER2 overexpressed breast tumor treated by chemotherapy and Trastuzumab showing a hypermetabolic retro-tracheal lymphadenopathy [15 × 17 mm and standardized uptake value (SUVmax) 4.5]. On the 18F-FDG PET-CT intermediate therapeutic assessment, there was a complete metabolic response except for the retro tracheal lymphadenopathy.…”

Section: Introductionmentioning

confidence: 99%

False Positive 18F-FDG Positron Emission Tomography Findings in Schwannoma—A Caution for Reporting Physicians

et al. 2018

View full text Add to dashboard Cite

Schwannoma is a rare source of false-positive 18F-fluorodeoxyglucose (18F-FDG) uptake in Positron-emission tomography (PET/CT), inducing potential errors in staging of several solid cancer, with implications for patient management. This clinical case reports the situation of a patient undergoing an 18F-FDG-PET/CT for initial staging of an ovarian adenocarcinoma. We found a high paramediastinal hypermetabolic mass suspicious of remote extension or secondary synchronous primitive tumor. The biopsy finally reveals a histopathology of Schwannoma, allowing the patient to be eligible for a surgical procedure of her ovarian adenocarcinoma by rejecting the hypothesis of malignancy.

show abstract

Mediastinal schwannoma mimicking lymph node metastasis from locally advanced breast cancer in a 18 F-FDG PET/CT study

Cited by 2 publications

References 3 publications

Retrospective analysis of the clinical presentation and imaging of eight primary benign mediastinal schwannomas

Retrospective analysis of the clinical presentation and imaging of eight primary benign mediastinal schwannomas

False Positive 18F-FDG Positron Emission Tomography Findings in Schwannoma—A Caution for Reporting Physicians

Contact Info

Product

Resources

About