Mediastinal lymphadenopathy and pulmonary arterial hypertension in mixed connective tissue disease.

Abstract

A case of mixed connective tissue disease (MCTD) is presented in which mediastinal lymphadenopathy was the most prominent radiological finding detected by plain chest radiographs and computed tomography. Pulmonary arterial hypertension, which is a rare and often fatal complication of MCTD, also developed in this patient.

Pulmonary Manifestations in Mixed Connective Tissue Disease

“…25 In two patients with MCTD, mediastinal lymphadenopathy has been described. 44,45 Biopsy of the enlarged lymph nodes showed nonspecific lymphoid reaction.…”