Mediastinal lipoblastoma with intraspinal extension: MRI demonstration

Ko, Sheung Fat; Shieh, Chie-Song; Shih, Teng-Yuan; Hsiao, Chih‐Cheng; Ng, Shu‐Hang; Lee, Tze‐Yu; Wan, Yung-Liang; Chen, Wei-Jen

doi:10.1016/s0730-725x(98)00015-0

Cited by 29 publications

(21 citation statements)

References 13 publications

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“…Although few cases of lipoblastomas located at the neck have been reported that result in a compression to the spinal cord [3][4][5], we are not aware of a previous report of a lipoblastomatous tumor with lipoblastomatosis nature presenting with paraparesis as a result of spinal cord compression.…”

Section: Introductionmentioning

confidence: 81%

“…The most common predilection sites of lipoblastomatous tumors are lower extremities in 32%, upper extremities in 18%, thorax in 18% and the head and neck region in 15% of the cases and other locations such as retroperitoneum, abdomen, parotid gland and tonsillar fossa [1,5]. A very recent review clarified that a total of 37 patients with cervical lipoblastomatous tumors located at the neck have been reported in the English literature [1].…”

Section: Discussionmentioning

confidence: 99%

“…Neurologic symptoms resulting from spinal cord compression are very rare. A total of three cases with lipoblastomas located at the neck showing symptoms of spinal cord compression have been reported previously [3][4][5]. Among these cases, one presented with hemiparesis [3], one with bilateral lower extremity paresis [5] and another with normal muscle strength [4].…”

Section: Discussionmentioning

confidence: 99%

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An unusual tumor of the neck and mediastinum: lipoblastomatosis resulting in paraparesis

Doğan

Kara

Firat

et al. 2007

European Journal of Cardio-Thoracic Surgery

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Lipoblastomatous tumors are quite rare neoplasms deriving from embryonic white fatty tissues, most often seen in infancy and childhood. Lipoblastoma is the focal and well-circumscribed type, whereas lipoblastomatosis is the more infiltrating type of lipoblastomatous tumors. We present a 14-month-old male infant presenting with a mediastinal mass showing paraparesis, who had previously undergone the removal of the cervical part of this mediastinal mass. We removed the mediastinal part of the mass with a posterolateral thoracotomy which proved to be a lipoblastomatosis. We emphasize that this very uncommon tumor located at the neck and mediastinum should be included in the differential diagnosis of infants having gait disturbance.

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Section: Introductionmentioning

confidence: 81%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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An unusual tumor of the neck and mediastinum: lipoblastomatosis resulting in paraparesis

Doğan

Kara

Firat

et al. 2007

European Journal of Cardio-Thoracic Surgery

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“…Several mediastinal lipoblastomatosis cases have been reported in which in ltration of the epidural and intraspinal space, phrenic nerve, and innominate vein occurred [ 13,14 ]. More recently, there have been lipoblastomatosis cases arising within the heart [ 28 ] and lung.…”

Section: Discussionmentioning

confidence: 99%

Lipoblastoma and Lipoblastomatosis in Infancy and Childhood: Histopathologic, Ultrastructural, and Cytogenetic Features

Hicks

Dilley

Patel

et al. 2001

Ultrastructural Pathology

105

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Lipoblastoma is a relatively rare tumor that occurs in infancy and early childhood and arises from embryonic white fat. Although a benign tumor, lipoblastomas tend to recur and may resemble myxoid liposarcoma. The authors report 26 cases over a 15-year period at Texas Children's Hospital. There was a slight female predilection (14F:12M). The most common symptom was a painless mass with or without increasing size. The trunk, extremities, head and neck, retroperitoneum, inguinal canal, peritoneal cavity, and lung were the tumor sites. Most tumors were circumscribed lipoblastomas and the minority were diffuse infiltrative lipoblastomatosis. Reexcision for residual or recurrent tumor was necessary more frequently in patients with lipoblastomatosis. Histopathologic examination and ultrastructural examination revealed cellular neoplasms composed of immature adipocytes with relatively well-defined septa, frequent lipoblasts, a fine vascular network, and often a myxoid appearance resembling myxoid liposarcoma. Cytogenetics was performed in 4 cases with chromosome 8q abnormality being most common. The major concern with lipoblastoma in children is to completely excise the tumor to avoid leaving residual tumor and to prevent recurrences. Confusion with myxoid liposarcoma, well-differentiated liposarcoma, and typical lipomas may occur. Although asymptomatic, lipoblastomas may cause dysfunction of other organ systems due to mass effect. Complete surgical excision with at least 2 years of follow-up is the preferred therapy.

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“…The magnetic resonance (MR) images may demonstrate intratumoral streaks and whorls consistent with the fibrous and vascular nature of the neoplasm. 2,14 The fat tissue emits high-signal intensity on both T1W and T2W images.…”

Section: Pathologic Featuresmentioning

confidence: 99%