Meconium Staining of the Amniotic Fluid. A Marker of Fetal Hypoxia

Brown, Clarence; Desmond, Murdina M.; Lindley, John; Moore, Jack

doi:10.1097/00006254-195706000-00020

Cited by 28 publications

(16 citation statements)

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“…194 (1982) Die "Lungenwaschung" ist die effektivste Maßnahme um dickes, zähes, mit den üblichen Methoden nur schwer entfernbares Material aus den Atemwegen des Kindes zu beseitigen. Lungenwaschungen werden auch bei anderen Krankheitsbildern mit Erfolg durchgeführt (6,9,23). Obgleich der Eingriff selbst zu einer vorübergehenden Beeinträchtigung des Patienten führt (4), ist der erzielte Effekt augenscheinlich (10,25,31…”

Section: Pädiatrisches Vorgehenunclassified

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Mekoniumhaltiges Fruchtwasser: Geburtshilflich-pädiatrisches Management zur Vermeidung des Mekoniumaspirationssyndromes

Rosegger¹,

Rosanelli²,

Hofmann³

et al. 1982

Klin Padiatr

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Section: Pädiatrisches Vorgehenunclassified

“…Mekoniumhaltiges Fruchtwasser (FW) wird in 5-10% aller Schwangerschaften gefunden. 1-3% der Neugeborenenoder 20% derjenigen, deren FW mekoniumhaltig war -weisen Zeichen eines Mekoniumaspirationssyndromes (MAS) auf (6,12,14). Die Letalität des MAS betrug vor der Ära der Intensivneonatologie etwa 28-30% der erkrankten Kinder (3,12).…”

Section: Introductionunclassified

Mekoniumhaltiges Fruchtwasser: Geburtshilflich-pädiatrisches Management zur Vermeidung des Mekoniumaspirationssyndromes

Rosegger¹,

Rosanelli²,

Hofmann³

et al. 1982

Klin Padiatr

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“…Another view is that of Desmond et al (1957), who considered meconium to be a marker for hypoxia and evidence that the foetus may become dangerously hypoxic during the remainder of the birth. In their series meconium was passed in 10.9% of cases: in these cases 77.2% of the babies had no difficulty in breathing at birth and in 22.8% there was difficulty of varying degree.…”

Section: Casementioning

confidence: 99%

Ante-partum Meconium Staining of the Liquor Amnii

Leslie¹

1959

BMJ

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“…Obstetricians have questioned the signifi cance of fetal meconium discharge and its effects upon the fetus and newborn [1,2], Fetal meconium discharge often accompanies alterations of blood flow associated with ute roplacental and fetoplacental events. Changes in fetal placental blood flow occur with pre eclampsia, hypertension, and intrauterine growth retardation [3].…”

Section: Introductionmentioning

confidence: 99%

In vitro Model of Human Umbilical Venous Pertusion to Study the Effects of Meconium Staining of the Umbilical Cord

Pickens

Toubas²,

Hyde³

et al. 1995

Neonatology

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Because meconium diffuses into placental and umbilical cord tissue, its bioactive components are potentially capable of entering the fetal circulation. Meconium diluted in Krebs solution produces vasocontraction in human umbilical vein segments that are suspended in a milieu similar to that of the amniotic cavity. Based on published observations, we wanted to determine if very diluted meconium could induce vasospasm in intact umbilical cords. Human umbilical cords were obtained from full-term deliveries, cut into 2 equal segments, cannulated, and perfused continuously as test and control cords. The study included four parts: (1) intraluminal meconium (n = 6; 0.01-1% solution); (2) 4-hour exposure to 10% meconium-stained amniotic fluid of intact umbilical cords (n = 8); (3) 4-hour exposure to a 10% meconium-stained amniotic fluid of umbilical cords denuded of their epithelial layer (n = 5); (4) 24-hour exposure to a 10% meconium-stained amniotic fluid of intact umbilical cords (n = 9). Significant vasoconstriction of the umbilical vein occurred only with the intraluminal meconium solution exposure (p = 0.034). In this in vitro model meconium staining of the umbilical cord was not associated with vasocontraction of the umbilical vein.

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Meconium Staining of the Amniotic Fluid. A Marker of Fetal Hypoxia

Cited by 28 publications

References 0 publications

Mekoniumhaltiges Fruchtwasser: Geburtshilflich-pädiatrisches Management zur Vermeidung des Mekoniumaspirationssyndromes

Mekoniumhaltiges Fruchtwasser: Geburtshilflich-pädiatrisches Management zur Vermeidung des Mekoniumaspirationssyndromes

Ante-partum Meconium Staining of the Liquor Amnii

In vitro Model of Human Umbilical Venous Pertusion to Study the Effects of Meconium Staining of the Umbilical Cord

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