2022
DOI: 10.3390/children9010035
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Meckel’s Diverticulum in Children: A Monocentric Experience and Mini-Review of Literature

Abstract: Vitelline duct anomalies (VDA, including Meckel’s diverticulum (MD)) result from failed embryologic obliteration. This study aimed for characteristics in symptomatic versus asymptomatic VDA, analyzing clinico-laboratory data from 73 children, aged 1 day to 17 years, treated at a tertiary Pediatric Surgery Institution from 2002–2017. A male preponderance was obtained (ratio 3.6:1). MD accounted for 85% of VDA. Incidence of symptomatic VDA decreased with older age. Leading symptoms were intestinal obstruction an… Show more

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Cited by 3 publications
(4 citation statements)
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“…Our data are globally concordant with the literature, even if 11% of MD were found beyond 60cm, suggesting the search of MD extended at least up 100 cm. At a variant of the literature [24,28], we could not demonstrate a correlation between age and distance from the ileocecal valve.…”
Section: Discussioncontrasting
confidence: 76%
See 1 more Smart Citation
“…Our data are globally concordant with the literature, even if 11% of MD were found beyond 60cm, suggesting the search of MD extended at least up 100 cm. At a variant of the literature [24,28], we could not demonstrate a correlation between age and distance from the ileocecal valve.…”
Section: Discussioncontrasting
confidence: 76%
“…Furthermore, our data showed no age differences comparing patients with intestinal bleeding and occlusion. On the contrary, it has been reported a younger mean age in children with intestinal obstruction, probably caused by the increased peristalsis due to the greater number of Auerbach plexus fibers present in young children [24]. The possibility to find an ectopic mucosa in the symptomatic MD is reported to be as high as 65-90% [25].…”
Section: Discussionmentioning
confidence: 99%
“…Meckel's diverticulum (MD) is a saccular formation present in the lower part of the intestine, and it is considered one of the most common congenital anomalies of the gastrointestinal tract [1,2]. It results from embryologic closure failure of the omphalomesenteric duct [3]. The protrusion of MD in a hernia sac is called a Littre hernia [2].…”
Section: Introductionmentioning
confidence: 99%
“…Dependendo da extensão e do local de desintegração e absorção, são várias as anomalias que podem resultar, incluindo OMD patente, cordões fibrosos do umbigo ao íleo, seio do ducto onfalomesentérico (umbilical) ou cisto em caso de persistência distal. No entanto, sua persistência na parte proximal constitui o representante mais comumente observado de anomalias do ducto vitelino, que é o divertículo de Meckel (Nissen et al, 2022).…”
Section: Introductionunclassified