Mechanochemical synthesis of some heterocyclic molecules using Sonogashira cross-coupling reaction and their anticancer activities

Chakraborty, Bhaskar; Chettri, Esmita

doi:10.1016/j.rechem.2020.100037

Cited by 2 publications

(2 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…-A correlation between the carbon C the proton H (9) . -A correlation between the carbon C the proton H (9') .…”

Section: -A Correlation Between the Carbon C The Proton H (8')mentioning

confidence: 99%

“…The biological interest [1,2,3] of these molecules is very broad and diversified. Several families of heterocyclic molecules are used as antiviral [4,5], anti tuberculosis [6,7], anti cancer [8,9,10], anti tuberculosis [11,12], anti malaria [13], anti fungus [14]. However, it is essential to have methods of analysis, which make it possible to elucidate the structure of these molecules.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Characterization of the Structure of 2-(4-methyl-2 Phenyl-4, 5-dihydrooxazol-4-ylmethyl)-isoindole-1, 3-dione by 1D, COSY and HSQC 2D NMR Spectroscopy

Dioukhane

Aouine²,

Nakkabi

et al. 2021

AJOCS

View full text Add to dashboard Cite

The identity of the 2-(4-Methyl-2-phenyl-4,5-dihydrooxazol-4-ylmethyl)-isoindole-1,3-dione, previously synthesized in our laboratory, was proven without doubt by means of 1D and 2D NMR spectroscopy. Two-dimensional NMR spectroscopy played a major role. The analysis of the 2D-COSY spectrum of isoindoline-1,3-dione derivative shows a perfect correlation between neighboring protons. Thus, a correlation was noted between the protons of the phthalimide, H(8) and H(9) on the one hand and H(8') and H(9') on the other hand. The analysis of the 2D-HSQC spectrum of the studied compound indicates a faultless correlation between protons and adjacent carbons, and no correlation in the case of all quaternary carbons.

show abstract

“…-A correlation between the carbon C the proton H (9) . -A correlation between the carbon C the proton H (9') .…”

Section: -A Correlation Between the Carbon C The Proton H (8')mentioning

confidence: 99%