Mechano‐Bactericidal Activities of Orthopedic Implants with Nanostructured Surfaces: Recent Advances and Prospects
Yuzheng Wu,
Pei Liu,
Paul K. Chu
Abstract:Orthopedic surgery enables patients to regain the functions of lost or damaged bone tissues, but success is often compromised by highly prevalent surgery site infections (SSIs). To prevent SSIs and avoid superbugs, mechano‐bactericidal strategies are being developed to inactivate bacteria on nanostructured surfaces based on contact killing. The antibacterial mechanism of nanostructured surfaces stems from the physical force exerted on the bacterial membrane while imposing lower lethality on host cells. Owing t… Show more
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