Mechanistic Study of the Effects of Different Dosages of Gemcitabine on the Migratory and Invasive Abilities of Lung Adenocarcinoma A549 Cells
Meng Wang,
Di Qiao,
Qiang Wang
Abstract:Lung adenocarcinoma is known to be a malignancy and a leading contributor to mortality. This research intended to delve into the impact of various dosages of gemcitabine on lung adenocarcinoma A549 and PC-9 cells proliferation, migration, and invasion. Additionally, the possible underlying mechanisms were also examined. An in vitro cell model was utilized in the experiment. Varying doses of gemcitabine (2.5, 5, 10 μM) were administered for treating A549 and PC-9 for 0 h-96 h. 3-(4,5-dimethylthiazol-2-yl)-2,5 d… Show more
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