Mechanistic Regulation of Planarian Shape During Growth and Degrowth
Jason M. Ko,
Waverly Reginato,
Daniel Lobo
Abstract:Adult planarians can grow when fed and degrow (shrink) when starved while maintaining their whole-body shape with correct proportions. Different planarian morphogens are expressed at the anterior-posterior poles, medio-lateral border, and midline to provide positional information signals for the specification of different tissues at the right locations. However, it is currently unknown how these signals are coordinated together during feeding or starvation and how they modulate the differential tissue growth o… Show more
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