Contributions to Nephrology 2004
DOI: 10.1159/000078877
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Mechanisms Underlying Combined Acute Renal Failure and Acute Lung Injury in the Intensive Care Unit

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Cited by 19 publications
(8 citation statements)
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“…In multiple organ dysfunction syndrome, ARF is an additional independent risk factor for mortality (28). It has been repeatedly demonstrated that there is a strong correlation between ARF and ARDS (6).…”
Section: Discussionmentioning
confidence: 99%
“…In multiple organ dysfunction syndrome, ARF is an additional independent risk factor for mortality (28). It has been repeatedly demonstrated that there is a strong correlation between ARF and ARDS (6).…”
Section: Discussionmentioning
confidence: 99%
“…27 When ARF and acute lung injury are combined, the mortality rate exceeds 80%. 28 Experimentally, ARF has been reported to induce caspase-dependent pulmonary apoptosis. 29 Patients with various renal diseases are particularly vulnerable to the adverse effects of PAP.…”
Section: Introductionmentioning
confidence: 99%
“…AKI and ARDS frequently coexist in critically ill patients, suggesting a shared pathophysiology (Chien et al. ; Liu et al. ; Vincent ).…”
Section: Introductionmentioning
confidence: 99%
“…Similar to ARDS, sepsis-induced acute kidney injury (AKI) is common and of great clinical significance, yet remains poorly understood (Uchino et al 2005;Zarjou and Agarwal 2011). AKI and ARDS frequently coexist in critically ill patients, suggesting a shared pathophysiology (Chien et al 2004;Liu et al 2007;Vincent 2011). We therefore hypothesized that sepsis is associated with activation of glomerular heparanase, contributing to the early onset of septic AKI.…”
Section: Introductionmentioning
confidence: 99%