Mechanisms of the Effects of Parental Emotional Warmth on Extraversion in Children and Adolescents

Li, Jing; Yao, Guanqun; Li, Xinrong; Zhao, Wentao; Du, Xinzhe; Wang, Xiao; Sun, Jingjing; Xu, Yong

doi:10.1016/j.neuroscience.2021.05.021

Cited by 5 publications

(3 citation statements)

References 52 publications

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“…Brain networks that facilitate systemic adaptation and flexibility are responsible for small-worldness ( 42 ) which is defined as the dynamic remodeling of the small-world topology and related community structure. Functional connectivity between the right precuneus and the right SFGdor was discovered by Li et al ( 43 ) to mitigate the mediating effects of small-worldness. Similarly, these findings are consistent with the hypothesis that the right SFGmed, SFGdor, and the left MFG all have a role in determining patient outcomes via processes analogous to small-worldness in MDD.…”

Section: Discussionmentioning

confidence: 97%

“…Rosalux et al ( 41 ) established a close relationship between the right SFG and the reappraisal of the emotional impact of particular events, with this ability and associated activity being linked to long-term mental health outcomes. Li et al ( 43 ) additionally found fALFF levels in the right precuneus and SFGdor to be significantly negatively correlated with extraverted behavior among adolescents and children, suggesting a role for the right SFGdor in the regulation of emotion. By combining imaging and genetic strategies, Yuan et al ( 44 ) further explored biomarkers linked to the diagnosis of MDD and to the prediction of therapeutic outcomes, ultimately establishing that relative to non-responding depression, responsive depression exhibited lower right SFGdor nodes, with the ALFF values in the bilateral occipital gyrus (MOG), left lentiform nuclear, right superior temporal gyrus, and the CBF in the right calcarine gyrus, and left caudate nucleus being significantly correlated with baseline MDD severity or early efficacy.…”

Section: Discussionmentioning

confidence: 98%

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Resting-state functional magnetic resonance imaging-based identification of altered brain the fractional amplitude of low frequency fluctuation in adolescent major depressive disorder patients undergoing electroconvulsive therapy

Wang

Tan²,

Li³

et al. 2022

Front. Psychiatry

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PurposeWhile electroconvulsive therapy (ECT) has been repeatedly been shown to effectively and efficiently treat the major depressive disorder (MDD), the mechanistic basis for such therapeutic efficacy remains to be firmly established. As such, further research exploring the ECT-based treatment of MDD in an adolescent population is warranted.MethodsThis study included 30 treatment-naïve first-episode MDD patients and 30 healthy control (HC) individuals (aged 12–17 years). All participants were scanned using rs-fMRI, and the 30 MDD patients were scanned again after 2 weeks of the ECT treatment period. Intrinsic local activity in each voxel was assessed based on the fractional amplitude of low frequency fluctuation (fALFF) parameter, with all fALFF analyses being completed using the REST application. Correlations between ECT-related changes in fALFF and clinical parameters were additionally examined.ResultsRelative to HCs, MDD patients exhibited increased fALFF values in the right inferior frontal gyrus (ORBinf), inferior occipital gyrus (IOG), and the left middle frontal gyrus (MFG) at baseline. Following ECT, these patients exhibited significant increases in fALFF values in the right medial superior frontal gyrus (SFGmed), dorsolateral superior frontal gyrus (SFGdor), anterior cingulate, and paracingulate gyrus (ACG), median cingulate and paracingulate gyrus (DCG), and left MFG. MDD patient HAMD scores were negatively correlated with fALFF values when analyzing pre-ECT vs. post-HCT ΔHAMD and fALFF values in the right SFGmed, SFGdor, and the left MFG.ConclusionThese data suggest that ECT induced altered fALFF in some regions of the brain, suggesting that these alterations may serve as a neurobiological indicator of ECT effectiveness in MDD adolescents.

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Section: Discussionmentioning

confidence: 97%

Section: Discussionmentioning

confidence: 98%

Resting-state functional magnetic resonance imaging-based identification of altered brain the fractional amplitude of low frequency fluctuation in adolescent major depressive disorder patients undergoing electroconvulsive therapy

Wang

Tan²,

Li³

et al. 2022

Front. Psychiatry

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show abstract

“…Confounding effects may stem from, for example, the shared genetic vulnerability for depression and Neuroticism (e.g., Kendler et al, 2019), or trait-like parenting factors such as emotional warmth, associated with both depression (Yang et al, 2008) and Extraversion (Li et al, 2021).…”

mentioning

confidence: 99%

Depression and Personality Traits Across Adolescence—Within-Person Analyses of a Birth Cohort

Morken,

Wichstrøm,

Steinsbekk

et al. 2024

Res Child Adolesc Psychopathol

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Depressive symptoms and personality traits covary in adolescents, but our understanding of the nature of this relation is limited. Whereas a predisposition explanation posits that specific personality traits increase the vulnerability for developing depression, a scar explanation proposes that depression may alter premorbid personality. Attempts to test these explanatory models have relied on analyses that conflate within-person changes and between-person differences, which limits the implications that can be drawn. Moreover, research on the early adolescent years is lacking. The present study therefore examined within-person associations between depressive symptoms and Big Five personality traits across ages 10 to 16. Children (n = 817; 49.9% boys) and parents from two birth cohorts in Trondheim, Norway, were assessed biennially with clinical interviews capturing symptoms of major depressive disorder and dysthymia, and self-reported Big Five personality traits. Analyses were conducted using a random intercept cross-lagged panel model, which accounts for all unmeasured time-invariant confounding effects. Increased Neuroticism predicted an increased number of depressive symptoms—and increased depressive symptoms predicted increased Neuroticism—across ages 10 to 14. Moreover, increased depressive symptoms forecast reduced Extraversion across ages 10 to 16, and reduced Conscientiousness from ages 12 to 14. Increases in Neuroticism may contribute to the development of depressive symptoms—in line with the predisposition model. As regards the scar model, depression may have an even wider impact on personality traits: increasing Neuroticism and reducing Extraversion and Conscientiousness. These effects may already be present in the earliest adolescent years.

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Using resting thalamic connectivity to identify the relationship between Eysenck personality traits and intelligence in healthy adults

Zhao

Qin

et al. 2022

Brain Research

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Mechanisms of the Effects of Parental Emotional Warmth on Extraversion in Children and Adolescents

Cited by 5 publications

References 52 publications

Resting-state functional magnetic resonance imaging-based identification of altered brain the fractional amplitude of low frequency fluctuation in adolescent major depressive disorder patients undergoing electroconvulsive therapy

Resting-state functional magnetic resonance imaging-based identification of altered brain the fractional amplitude of low frequency fluctuation in adolescent major depressive disorder patients undergoing electroconvulsive therapy

Depression and Personality Traits Across Adolescence—Within-Person Analyses of a Birth Cohort

Using resting thalamic connectivity to identify the relationship between Eysenck personality traits and intelligence in healthy adults

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