Abstract:Three modes of PCP -induced membrane electrical conductivity were theoretically analyzed and experimentally verifiable formulations of each models were developed. Experimental studies using the charge -pulse method involved characterization of the time dependent transmembrane voltage over a wide pH range, from 1.8 to 9.5, for 30 p.M concentrations of PCP. Lipid membranes were prepared from dioleoyl phosphatidylcholine.
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