Mechanisms of hydrogel-based microRNA delivery systems and its application strategies in targeting inflammatory diseases
Shaorun Hu,
Yu Liang,
Jinxiang Chen
et al.
Abstract:Hydrogels, composed of three-dimensional polymer networks, are excellent delivery carriers and have been extensively employed in the biomedical field. Inflammation acts as a protective mechanism to prevent harmful substances from entering living organisms, but chronic, long-lasting inflammation can cause oxidative stress, which damages tissue and organs and adversely affects patients’ quality of life. The aberrant expression of microRNAs (miRNAs) has been found to play a significant part in the etiology and pr… Show more
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