Mechanisms of formation of airway hyperreactivity in view of phenotypical heterogeneity and clinical deviation of bronchial asthma in adolescents (literature review)
Abstract:Bronchial asthma is a disease characterized by recurrent episodes of variable bronchial obstruction, chronic bronchial inflammation, bronchial hypersensitivity and remodulation. Modern therapy of the disease was aimed at these links of pathogenesis, and this concept postulated the need for long-term use of anti-inflammatory drugs and, above all, topical inhaled corticosteroids. However, it should be recognized that the coherent inflammatory theory currently requires revision and new understanding, or even repl… Show more
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