Mechanisms of Formation and Persistence of Ige Products and Potential Innovative Means of Therapy for Allergic Pathologies
D. B. Chudakov,
M. V. Konovalova,
M. A. Streltsova
et al.
Abstract:The proposed review is devoted to the analysis of the main mechanisms of the formation of IgE-producing cells in the body and a brief review of the main, most striking candidate agents for use in innovative methods of therapy for IgE-dependent pathologies. Data are presented according to which the role of IgE+ plasma cells and various subpopulations of memory B-lymphocytes in the formation and persistence of the state of sensitization to a harmless allergen differs depending on the model system used or the cli… Show more
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