Mechanisms of axoneme and centriole elimination inNaegleria gruberi
Alexander Woglar,
Coralie Busso,
Gabriela Garcia-Rodriguez
et al.
Abstract:The excavate Naegleria gruberi, a basal eukaryote related to the "brain eating" Naegleria fowleri, can transform transiently from an amoeboid life form lacking flagella and centrioles to a flagellate life form where these elements are present, followed by reversion to an amoeboid state. The mechanisms imparting elimination of axonemes and centrioles during this reversion process are not known. Here, we uncover that flagella primarily fold onto the cell surface and fuse within milliseconds with the plasma membr… Show more
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