Mechanism of traumatic neuroma development

Successful Treatment of Traumatic Neuroma

“…Their results clearly correspond to our hypothesis postulating that traumatic neuroma development involves simultaneous nerve repair and defensive mechanisms (i.e., reactive proliferation of perineurial cells) in the region of concomitant wound and scar contraction [2]. Moreover, by their surgical approach, they disrupted the proposed ''easily violable balance between nerve regeneration and damage'' [2] and obtained a long-term treatment effect. In conclusion, I would like to congratulate the authors on their results, which reflect their top-rated skills, necessary to perform a meticulous surgery in the field of previous operation.…”

Postoperative Imaging and Surveillance in Large Nerve Perineural Spread

“…Traumatic neuromas are well described in other locations in the body and are nonneoplastic lesions created by disorganized proliferation of nerves at the site of surgery. 12 At initial surveillance imaging in patients with clear pathological margins, there is often a focal nodule of enhancement that occurs at the point of nerve resection. For example, patients who have zone 1 disease of the infraorbital nerve usually undergo resection of the nerve at the foramen rotundum.…”

Ultrasonographic features of traumatic neuromas in breast cancer patients after mastectomy

“…Traumatic neuromas are rare benign lesions that occur at the proximal end of a severed nerve [1]. They are not true neoplasms but hyperplastic proliferations of neuronal and connective tissue that occur in response to nerve injury [1].…”

“…They are not true neoplasms but hyperplastic proliferations of neuronal and connective tissue that occur in response to nerve injury [1]. They can occur in any part of the body that has been subjected to trauma or surgery, but most commonly occur in the lower extremities after amputation procedures, followed by the head and neck [2].…”