Mechanism of Sodium Valproate Combined with Decitabine in Inhibiting Hepatocellular Carcinoma Cells Epithelial-Mesenchymal Transition and Invasion and Metastasis Based on p38 Mitogen-Activated Protein Kinases/Heat Shock Protein 27 Regulating Proliferation by p53 Pathway
Abstract:Gao et al.: Mechanism of Sodium Valproate Combined with Decitabine in Inhibiting Hepatocellular Carcinoma Cells Sodium valproate combined with decitabine can inhibit cancer by inhibiting the invasion and metastasis of liver cancer cells of which the mechanism is not yet clear. In this study, valproic acid and decitabine were used during the culture of liver cancer cell that is human hepatocarcinoma cell line SMMC-7721 and the p38 mitogen-activated protein kinase activator anisomycin was added. Western blot was… Show more
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