Mechanism of action of adapalene for treating EGFR‐TKI‐induced skin disorder
Chihiro Mimura,
Tatsuya Nagano,
Nanako Miwa
et al.
Abstract:BackgroundSkin disorders are the most common side effect associated with epidermal growth factor receptor‐tyrosine kinase inhibitor (EGFR‐TKI) therapy. It is important to manage skin lesions. Adapalene has been used to treat skin lesions caused by EGFR‐TKIs in some cases. The aim of this study was to investigate the functional mechanism of adapalene in erlotinib‐induced skin disorder.MethodsTo analyze the effect of adapalene on skin rash, afatinib and adapalene were administered to mice. The relationship betwe… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.