Mechanism of a case of genetic coadaptation in populations of Drosophila melanogaster.

Hartl, Daniel L.

doi:10.1073/pnas.74.1.324

Cited by 10 publications

(6 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…While this phenomenon was first discussed over 40 years ago (Dobzhansky, 1950(Dobzhansky, , 1970Hedrick et al, 1978), little progress has been made in understanding the genetic mechanisms under-lying hybrid breakdown. Hartl's (1977) analysis of the segregation distorter system in natural Drosophila melanogaster populations remains perhaps the only example of hybrid breakdown (of segregation ratio) where the intergenic interactions can be ascribed to mapped gene loci; however, even in this system, the biochemical and molecular mechanisms remain unknown.…”

mentioning

confidence: 99%

Hybrid Breakdown in Physiological Response: A Mechanistic Approach

Burton

1990

Evolution

View full text Add to dashboard Cite

Data comparing the physiological response to hyperosmotic stress in individual copepods (Tigriopus californicus) from natural populations and laboratory hybrids are presented. While individuals from two genetically differentiated natural populations and F interpopulation hybrids showed only minor differences in patterns of free amino acid (FAA) accumulation during hyperosmotic stress, patterns of FAA synthesis were highly variable among the F hybrids. Isofemale lines initiated from later hybrid generations (F -F ) exhibited substantial inter-line variance in FAA accumulation. This increased variance in physiological response appears unrelated to allozyme polymorphisms at two loci encoding FAA-metabolizing enzymes and appears to result from other, unidentified polymorphisms in the proline synthetic pathway.

show abstract

mentioning

confidence: 99%

Hybrid Breakdown in Physiological Response: A Mechanistic Approach

Burton

1990

Evolution

View full text Add to dashboard Cite

show abstract

“…The genetic mechanisms responsible for hybrid breakdown have not been extensively detailed. Hartl's (1977) analysis ofthe segregation-distorter system in natural D. melanogaster populations remains perhaps the only example of the hybrid breakdown of a presumably adaptive trait (segregation ratio) where the intergenic interactions can be ascribed to mapped gene loci. Presumably, breakdown of fitness-related traits in general is a consequence of "incompatibilities" between differentiated parts ofthe parental genomes, although genome-cytoplasm interactions may also have important effects (e.g., Hiraizumi, 1985).…”

mentioning

confidence: 99%

DIFFERENTIATION AND INTEGRATION OF THE GENOME IN POPULATIONS OF THE MARINE COPEPOD TIGRIOPUS CALIFORNICUS

Burton

1987

Evolution

View full text Add to dashboard Cite

Geographically separated populations of the intertidal copepod Tigriopus californicus are sharply differentiated at several enzyme-encoding gene loci. Two studies were performed to investigate the extent to which the gene pools of local populations are organized into harmoniously interacting (or "coadapted") gene complexes. In the first, the effects of interpopulation hybridization on development time were assessed. Results showed that while F hybrids did not differ from parental lines, mean F developmental times were as much as 50% longer. The second study used two unlinked enzyme polymorphisms as genetic markers to determine the genotypic specificity of F hybrid breakdown. For two sets of parental populations, the relative viabilities of the different two-locus genotypes were determined from segregation ratios among the F progeny. Sharp deviations from Mendelian ratios were observed; in the extreme, a block of genes marked by the Me allozyme from the LJ (La Jolla) population was found to be nearly lethal when homozygous in the F of LJ × AB (Los Angeles) crosses. This same block of genes had a tenfold higher viability in crosses between LJ and SC (Santa Cruz). In the AB × LJ crosses, the two marker loci had independent (multiplicative) effects on viability. In the SC × LJ crosses, deviations from the multiplicative model were observed; the data indicate that parental homozygous genotypes have higher viability than predicted by independence, while nonparental homozygotes have lower than predicted viability. These results suggest that substantial integration of the genome has occurred within natural T. californicus populations.

show abstract

“…This process is analogous to the accumulation of modifiers of the meiotic drive acting on sex-ratio distorter or segregation distorter genes in the experiments of, for example, Hartl (1977) and Lyttle (1979). Hence, the observation of a polymorphism for meiotic drive in an experiment on the inheritance of transmission rates (Shaw and Hewitt, in press) is of considerable interest.…”

Section: Introductionmentioning

confidence: 99%

Polymorphism in the rates of meiotic drive acting on the B-chromosome of Myrmeleotettix maculatus

1985

View full text Add to dashboard Cite

A survey of all the available data on meiotic transmission rates in M. maculatus suggests that a polymorphism in female transmission rate exists in most natural populations. Differences in the frequency of the types or in the transmission rates they manifest may exist between populations or over time, but the evidence is not compelling. The data on males are also equivocal, especially because the environment may affect male transmission rate. We suggest that the polymorphism in female rates may demonstrate the selective equilibrium between the B and the genome in which it exists.

show abstract

Mechanism of a case of genetic coadaptation in populations of Drosophila melanogaster.

Abstract: A crtic polymorphism found in natural populations of Drosophila melanogaster has been examined in an artificial population maintained for over MOO generations.

Cited by 10 publications

References 14 publications

Hybrid Breakdown in Physiological Response: A Mechanistic Approach

Hybrid Breakdown in Physiological Response: A Mechanistic Approach

DIFFERENTIATION AND INTEGRATION OF THE GENOME IN POPULATIONS OF THE MARINE COPEPOD TIGRIOPUS CALIFORNICUS

Polymorphism in the rates of meiotic drive acting on the B-chromosome of Myrmeleotettix maculatus

Contact Info

Product

Resources

About