Mechanism Investigation of Tianxiangdan Against Myocardial Ischemia Based on Network Pharmacology, Molecular Docking, and in vitro Experimental
Lin Jiang,
Yuan-Jia Yue,
Mei Tang
et al.
Abstract:Objectives: Tianxiangdan capsule (TXD) has been clinically used in the treatment of coronary heart disease angina pectoris. This study aimed to evaluate the mechanisms of TXD against myocardial ischemia and provide evidence for its subsequent clinical application. Materials and Methods: Active components and mechanisms of action of TXD against myocardial ischemia were predicted and analyzed by network pharmacology and molecular docking. The chemical constituents in TXD were determined by HPLC-MS. The oxidativ… Show more
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