Swinburne AJ, Fedullo AJ, Shayne DS. Mechanical ventilation: analysis of increasing use and patient survival. J Intensive Care Med 1988;3:315-320.To quantitate and assess an increase in the use of mechanical ventilation, we retrospectively analyzed the records of 1,589 patients treated with mechanical ventilation. Between 1974 and 1983, there was a 156% increase in the number of patients treated each year.There were significant increases in the number of patients with cardiac pulmonary edema (p < 0.001), adult respiratory distress syndrome (p < 0.01), chronic obstructive lung disease (p < 0.005), neuromuscular disease (p < 0.025), and cardiopulmonary arrest (p < 0.005). Regression analysis versus time shows that older patients (p < 0.025) and more chronically ill patients (p < 0.05) are now being treated with mechanical ventilation. Overall survival was 41.4%, and yearly survival rates remained constant during the ten-year period. Survival was 55.3% for patients with cardiogenic pulmonary edema, 34.1 % for the adult respiratory distress syndrome, 65.7% for chronic obstructive lung disease, 90.5% for asthma, 38.7% for neuromuscular disease, 92.1% for drug overdose, 33.7% for pneumonia, and 19.1 % for cardiopulmonary arrest. Studies are needed that will determine predictors of survival from acute respiratory failure for patients with chronic heart and lung disease. Such predictors will help physicians counsel their patients when making the decision to be treated with mechanical ventilation in the event of respiratory failure.Mechanical ventilation saves many lives by making recovery from respiratory failure possible. It is also a costly therapy [1] ] that may sustain life when recovery can no longer occur [2]. As pressures mount to limit the costs of medical care and concerns increase about prolonging life in the hopelessly ill, careful scrutiny of the use of mechanical ventilation becomes increasingly important.Since 1980, Rochester, NY, hospitals have been funded by an experimental prospective reimbursement system based on 1978 costs [3]. Budgetary restrictions imposed by this system made it difficult for our hospital to allocate funds for the personnel and equipment needed to care for an increasing number of patients requiring mechanical ventilation. This focused our attention on the issue of increased use of mechanical ventilation. Several explanations for this increase were proposed, including a change in diagnostic case mix and more aggressive use of mechanical ventilation in the treatment of aged or chronically ill patients.To quantitate the increase and to test our hypotheses about case mix changes and changing physician practice patterns, we reviewed the medical records of all patients treated with mechanical ven-