Mechanical ventilation of patients on long-term oxygen therapy with acute exacerbations of chronic obstructive pulmonary disease: prognosis and cost-utility analysis

Abstract

Applying mechanical ventilation to COPD patients treated with long-term oxygen therapy carries a high mortality and cost. Factors significantly associated with mortality in the ICU were albumin and sodium concentrations and FEV1 in hospital and in the first year after discharge.

Intensive Care Cost Analysis Of Patients With Acute Exacerbations Of Chronic Obstructive Pulmonary Diseases From Two University Hospitals

“…There was statistically significant difference (p<0.05). We found that the mortality rate was 42.9%, this result was higher than previous studies, [8,9,11,12,14,15] but in our study all of the patients had respiratory failure and had mechanical ventilation.…”

“…Añón et al [8] found that comorbid diseases were presented in 8 patients of 20 patients. Chen et al [10] demonstrated that 204 of 439 patients had respiratory failure, 153 had cor pulmonale, 123 had coronary artery disease, 231 had hypertension, 70 had cerebrovascular disease and 32 had renal failure.…”

“…[8][9][10][11][12][13][14][15] Añón et al [8] analysed the prognosis and costs of mechanical ventilation in patients with exacerbations of COPD in an university hospital ICU. They found that the mean age was 64 years (44-77).…”

“…[8][9][10][13][14][15] Añón et al [8] evaluated 206 admissions due to COPD, 20 patients met the inclusion criteria of their study and demonstrated that the total cost in the ICU was U.S. $1359061, with a mean cost per patient of U.S. $67953. They did not demonstrate the composition of intensive care costs.…”

“…[6,7] Even though cost studies have been conducted in some countries, [8][9][10][11][12][13][14][15] the detailed cost of acute exacerbations of COPD in ICU in Turkey has not been studied.…”